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Spots Global Cancer Trial Database for A Study of Avastin (Bevacizumab) Added to Interferon Alfa-2a (Roferon) Therapy in Patients With Metastatic Renal Cell Cancer With Nephrectomy

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Trial Identification

Brief Title: A Study of Avastin (Bevacizumab) Added to Interferon Alfa-2a (Roferon) Therapy in Patients With Metastatic Renal Cell Cancer With Nephrectomy

Official Title: A Randomised, Double-blind Study to Evaluate the Efficacy and Safety of Avastin Plus Roferon Compared With Placebo Plus Roferon on Overall Survival and Tumor Assessment in Nephrectomised Patients With Metastatic Clear Cell Renal Cell Carcinoma

Study ID: NCT00738530

Study Description

Brief Summary: This 2-arm study will evaluate the efficacy and safety of Avastin versus placebo in combination with Roferon as first-line treatment in participants with metastatic renal cell cancer (clear cell type) who have had nephrectomy. The anticipated time of study treatment is 1-2 years, and the target sample size is greater than (\>)500 individuals.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

, Adelaide, , Australia

, Adelaide, , Australia

, Brisbane, , Australia

, Canberra, , Australia

, Frankston, , Australia

, Kurralta Park, , Australia

, Melbourne, , Australia

, Perth, , Australia

, Sydney, , Australia

, Sydney, , Australia

, Antwerpen, , Belgium

, Bruxelles, , Belgium

, Bruxelles, , Belgium

, Wilrijk, , Belgium

, Ceské Budejovice, , Czech Republic

, Chomutov, , Czech Republic

, Hradec Kralove, , Czech Republic

, Plzen, , Czech Republic

, Tampere, , Finland

, Turku, , Finland

, Angers, , France

, Bordeaux, , France

, Caen, , France

, Clermont Ferrand, , France

, Grenoble, , France

, Lille, , France

, Limoges, , France

, Lyon, , France

, Marseille, , France

, Nice, , France

, Poitiers, , France

, Saint Herblain, , France

, Strasbourg, , France

, Suresnes, , France

, Toulouse, , France

, Villejuif, , France

, Berlin, , Germany

, Darmstadt, , Germany

, Hamburg, , Germany

, Hannover, , Germany

, Mannheim, , Germany

, Marburg, , Germany

, München, , Germany

, Planegg, , Germany

, Budapest, , Hungary

, Szombathely, , Hungary

, Holon, , Israel

, Ramat-gan, , Israel

, Rehovot, , Israel

, Tel Aviv, , Israel

, Zerifin, , Israel

, Livorno, , Italy

, Milano, , Italy

, Milano, , Italy

, Modena, , Italy

, Napoli, , Italy

, Perugia, , Italy

, Roma, , Italy

, Rozzano, , Italy

, Torino, , Italy

, Amsterdam, , Netherlands

, Nijmegen, , Netherlands

, Oslo, , Norway

, Stavanger, , Norway

, Trondheim, , Norway

, Ålesund, , Norway

, Bydgoszcz, , Poland

, Krakow, , Poland

, Lodz, , Poland

, Olsztyn, , Poland

, Tarnow, , Poland

, Warszawa, , Poland

, Moscow, , Russian Federation

, Moscow, , Russian Federation

, Moscow, , Russian Federation

, Moscow, , Russian Federation

, Moscow, , Russian Federation

, Moscow, , Russian Federation

, Obninsk, , Russian Federation

, St Petersburg, , Russian Federation

, St Petersburg, , Russian Federation

, Singapore, , Singapore

, Singapore, , Singapore

, Barcelona, , Spain

, Barcelona, , Spain

, Barcelona, , Spain

, Granada, , Spain

, Madrid, , Spain

, Madrid, , Spain

, Málaga, , Spain

, Pontevedra, , Spain

, Santander, , Spain

, Valencia, , Spain

, Zaragoza, , Spain

, Basel, , Switzerland

, Bern, , Switzerland

, Geneve, , Switzerland

, Chang Gung, , Taiwan

, Kaohsiung, , Taiwan

, Taichung, , Taiwan

, Taipei, , Taiwan

, London, , United Kingdom

, London, , United Kingdom

, Manchester, , United Kingdom

Contact Details

Name: Clinical Trials

Affiliation: Hoffmann-La Roche

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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