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Spots Global Cancer Trial Database for A Study of Avastin (Bevacizumab) in Combination With Standard Therapy in Patients With Metastatic Renal Cell Cancer.

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Trial Identification

Brief Title: A Study of Avastin (Bevacizumab) in Combination With Standard Therapy in Patients With Metastatic Renal Cell Cancer.

Official Title: An Open-label Study to Assess the Effect of First-line Treatment With Avastin in Combination With Standard Therapy on Progression-free Survival in Patients With Metastatic Renal Cell Cancer.

Study ID: NCT00520403

Study Description

Brief Summary: This single arm study will assess the efficacy and safety of Avastin in combination with interferon alfa-2a and vinblastine as first line treatment in patients with metastatic renal cell cancer. Patients will receive Avastin (15mg/kg iv) every 3 weeks, interferon alfa-2a 3 times weekly (3 Mio IU sc escalating to 18 Mio sc) and vinblastine (0.1mg/kg iv) every 3 weeks. The anticipated time on study treatment is until tumor progression, and the target sample size is 100-500 individuals.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

, Berlin, , Germany

, Berlin, , Germany

, Bremen, , Germany

, Dessau, , Germany

, Erlangen, , Germany

, Frankfurt, , Germany

, Halle, , Germany

, Hannover, , Germany

, Jena, , Germany

, Kassel, , Germany

, Kiel, , Germany

, Leipzig, , Germany

, Magdeburg, , Germany

, Rehling, , Germany

, Stuttgart, , Germany

, Weiden, , Germany

Contact Details

Name: Clinical Trials

Affiliation: Hoffmann-La Roche

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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