Spots Global Cancer Trial Database for A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003)
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Trial Identification
Brief Title: A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003)
Official Title: A Phase 2 Trial of PT2977 in Combination With Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
Study ID: NCT03634540
Study Description
Brief Summary: This is an open-label Phase 2 study which will evaluate the efficacy and safety of belzutifan in combination with cabozantinib in participants with advanced ccRCC. Belzutifan and cabozantinib will be administered orally once daily.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
USC Norris Comprehensive Cancer Center ( Site 0060), Los Angeles, California, United States
Cedars Sinai Medical Center Samuel Oschin Comp. Cancer Institute ( Site 0003), Los Angeles, California, United States
Sylvester Comprehensive Cancer Center ( Site 0023), Miami, Florida, United States
Dana Farber Cancer Center ( Site 0006), Boston, Massachusetts, United States
Karmanos Cancer Institute ( Site 0033), Detroit, Michigan, United States
Tennessee Oncology, PLLC ( Site 0024), Chattanooga, Tennessee, United States
Tennessee Oncology, PLLC ( Site 0001), Nashville, Tennessee, United States
Texas Oncology-Baylor Charles A. Sammons Cancer Center ( Site 0010), Dallas, Texas, United States
Swedish Cancer Institute ( Site 0018), Seattle, Washington, United States
Seattle Cancer Care Alliance/Univ of Washington Medical Center ( Site 0035), Seattle, Washington, United States
Contact Details
Name: Medical Director
Affiliation: Merck Sharp & Dohme LLC
Role: STUDY_DIRECTOR
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