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Brief Title: Outcome-related Factors in Patients With Metastatic Renal Cell Carcinoma Treated With Everolimus (ORCHIDEE)
Official Title: Outcome-related Factors in Patients With Metastatic Renal Cell Carcinoma Treated With Everolimus After Failure of a First-line Treatment With VEGF Inhibitor
Study ID: NCT02338570
Brief Summary: Evaluation of unfavourable outcome-related factors in patients affected by renal cell cancer in treatment with everolimus and previously treated with a Vascular endothelial growth factor (VEGF) inhibitor (i.e. sunitinib, sorafenib,pazopanib, or bevacizumab+interferon)
Detailed Description: Predictive factors to be considered are: histology, Heng risk group, Eastern Cooperative Oncology Group-performance status (ECOG-PS), site of metastases, glycemia and cholesterolemia. The data collected in this "real life" population could contribute to identify clinical factors that predict favourable outcomes in patients treated with everolimus after failure or a a first-line treatment with a VEGF inhibitor.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Spedali Civili, Brescia, , Italy
Ospedale A Perrino, Brindisi, , Italy
Istituto Europeo di Oncologia, Milano, , Italy
Istituto Nazionale Tumori - IRCCS Fondazione G. Pascale, Napoli, , Italy
AOU Maggiore della Carità, Novara, , Italy
Casa di Cura La Maddalena, Palermo, , Italy
Unicampus Biomedico, Roma, , Italy
AOU San Giovanni di Dio e Ruggi D'Aragona, Salerno, , Italy
Name: Giacomo Cartenì
Affiliation: Azienda Ospedaliera "Antonio Cardarelli", Napoli
Role: PRINCIPAL_INVESTIGATOR