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Brief Title: A Phase 1b Study of SGN-75 in Combination With Everolimus in Patients With Renal Cell Carcinoma
Official Title: A Phase 1b, Open-label, Dose-escalation Study to Evaluate the Safety and Tolerability of SGN-75 in Combination With Everolimus in Patients With CD70-positive Metastatic Renal Cell Carcinoma
Study ID: NCT01677390
Brief Summary: This is a phase 1, open-label, dose-escalation clinical trial to evaluate the safety of SGN-75 in combination with everolimus in patients with CD70-positive metastatic renal cell carcinoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Stanford Cancer Center, Stanford, California, United States
Rocky Mountain Cancer Centers - Midtown, Denver, Colorado, United States
Karmanos Cancer Institute / Wayne State University, Detroit, Michigan, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
UNC Lineberger Comprehensive Cancer Center / University of North Carolina, Chapel Hill, North Carolina, United States
Miriam Hospital, The, Providence, Rhode Island, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States
Seattle Cancer Care Alliance / University of Washington, Seattle, Washington, United States
Name: Elaina Gartner, MD
Affiliation: Seagen Inc.
Role: STUDY_DIRECTOR