Spots Global Cancer Trial Database for Significance of Immunohistochemical Expression of Survivin in Renal Cell Carcinoma
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Trial Identification
Brief Title: Significance of Immunohistochemical Expression of Survivin in Renal Cell Carcinoma
Official Title: A Retrospective Study
Study ID: NCT04873180
Conditions
Study Description
Brief Summary: detection of Survivin expression in renal cell carcinoma and correlate this expression to tumor grade and stage.
Detailed Description: renal cell carcinoma is the third most prevalent malignant tumor of the genitourinary system. deregulation of apoptosis is involved in carcinogenesis by abnormally prolonged cell survival, facilitating accumulations of multiple mutations and augment resistance to immune-surveillance. Survivin is a member of inhibitor of Apoptosis Protein family (IAPs). it play a role in cell cycle regulation by inhibiting apiptosis. Survivin is over-expressed in many human neoplasms.
Eligibility
Minimum Age: 30 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Maisa Hashem Mohammed, Sohag, , Egypt
Contact Details
Name: Maisa H Mohammed, MD
Affiliation: a lecturer of pathology, Sohag faculty of medicine
Role: PRINCIPAL_INVESTIGATOR
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