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Brief Title: Trial of NanoDoce Intratumoral Injection in Renal Cell Carcinoma
Official Title: Phase 1 Trial Evaluating the Safety and Tolerability of NanoDoce® Intratumoral Injection in Subjects With Localized Renal Cell Carcinoma
Study ID: NCT04260360
Brief Summary: This study evaluates the use of NanoDoce injected directly into tumors in the kidney of people with renal cell carcinoma.
Detailed Description: NanoDoce is very small (submicron) particles of the chemotherapy drug, docetaxel, which is administered intravenously in a number of types of cancer. These submicron particles are injected directly into solid tumors to target cancer at the site of disease with less systemic exposure than intravenously administered chemotherapy. In this study, the submicron particle docetaxel will be injected directly into tumors in the kidney of people with renal cell carcinoma that is localized to (has not spread beyond) the kidney. All subjects in this study will receive NanoDoce and will be evaluated to see if NanoDoce is safe.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Name: Rose Marie Cavanna-Mast, RT, CCRA
Affiliation: US Biotest, Inc.
Role: STUDY_DIRECTOR