Spots Global Cancer Trial Database for Efficacy and Safety Comparison of RAD001 Versus Sunitinib in the First-line and Second-line Treatment of Patients With Metastatic Renal Cell Carcinoma
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Trial Identification
Brief Title: Efficacy and Safety Comparison of RAD001 Versus Sunitinib in the First-line and Second-line Treatment of Patients With Metastatic Renal Cell Carcinoma
Official Title: An Open-label, Multicenter Phase II Study to Compare the Efficacy and Safety of RAD001 as First-line Followed by Second-line Sunitinib Versus Sunitinib as First-line Followed by Second-line RAD001 in the Treatment of Patients With Metastatic Renal Cell Carcinoma.
Study ID: NCT00903175
Conditions
Study Description
Brief Summary: This study assessed the efficacy and safety of first-line RAD001 followed by second-line sunitinib versus the opposite sequence: first-line sunitinib followed by second-line RAD001 for the treatment of patients with MRCC.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Alabama at Birmingham/ Kirklin Clinic Comprehensive CancerCenter (1), Birmingham, Alabama, United States
University of South Alabama / Mitchell Cancer Institute Dept. of Mitchell Cancer Inst., Mobile, Alabama, United States
Highlands Oncology Group HighlandsOncGrp-Bentonville(2), Fayetteville, Arkansas, United States
University of California San Diego - Moores Cancer Center Dept of Moores Cancer Ctr (5), La Jolla, California, United States
University of California at Los Angeles Dept. of UCLA (3), Los Angeles, California, United States
University of Colorado Dept. of Anschutz Cancer (2), Aurora, Colorado, United States
Norwalk Hospital Norwlak SC, Norwalk, Connecticut, United States
Georgetown University/Lombardi Cancer Center Dept.of Lombardi Cancer Ctr (2, Washington, District of Columbia, United States
Lynn Cancer Institute, Boca Raton, Florida, United States
University of Miami SC, Miami, Florida, United States
MD Anderson Cancer Center - Orlando Dept.ofMDACC-Orlando, Orlando, Florida, United States
University Cancer & Blood Center, LLC Dept of NE GCC (2), Athens, Georgia, United States
Georgia Health Sciences University Dept. of MCG, Augusta, Georgia, United States
Summit Cancer Care, Savannah, Georgia, United States
NorthwesternUniv.Med.School/Robert H. Lurie Comp.Cancer Ctr Dept.ofNorthwesternMemHospital, Chicago, Illinois, United States
Loyola University Medical Center /Cardinal Bernardin Cancer Cardinal Bernardin Cancer (3), Maywood, Illinois, United States
Crescent City Research Consortium, LLC SC, Metairie, Louisiana, United States
VA Maryland Health Care Dept.of GreenbaumCancerCent(7), Baltimore, Maryland, United States
Weinberg Cancer Institute at Franklin Square Hospital, Baltimore, Maryland, United States
Billings Clinic Dept of Billings Clinic(2), Billings, Montana, United States
Hackensack University Medical Center DeptofHackensackUniv.MedCtr., Hackensack, New Jersey, United States
Cooper Cancer Center, Voorhees, New Jersey, United States
Clinical Research Alliance, Lake Success, New York, United States
Memorial Sloan Kettering Cancer Center Dept. of MSKCC, NY, New York, United States
SUNY - Upstate Medical University Div. of Hematology-Oncology, Syracuse, New York, United States
University of North Carolina Dept. of LinbergerCancerCtr(3), Chapel Hill, North Carolina, United States
Levine Cancer Institute Oncology, Charlotte, North Carolina, United States
Duke University Medical Center Duke, Durham, North Carolina, United States
University of Oklahoma Health Sciences Center Dept of OHSC, Oklahoma City, Oklahoma, United States
St. Luke's Hospital and Health Network St Luke's Hospital (2), Bethlehem, Pennsylvania, United States
The West Clinic Dept. of the West Clinic, Memphis, Tennessee, United States
The Center for Cancer and Blood Disorders Dept. of The Ctr for C & BD(2), Fort Worth, Texas, United States
East Texas Medical Center Cancer Institute, Tyler, Texas, United States
Utah Cancer Specialists Dept.of Utah Cancer Spec. (3), Salt Lake City, Utah, United States
Aurora Advanced Healthcare SC, Milwaukee, Wisconsin, United States
Novartis Investigative Site, Caba, Buenos Aires, Argentina
Novartis Investigative Site, La Plata, Buenos Aires, Argentina
Novartis Investigative Site, Rosario, Santa Fe, Argentina
Novartis Investigative Site, Tucuman, , Argentina
Novartis Investigative Site, Woodville, South Australia, Australia
Novartis Investigative Site, Rio de Janeiro, RJ, Brazil
Novartis Investigative Site, Porto Alegre, RS, Brazil
Novartis Investigative Site, Sao Paulo, SP, Brazil
Novartis Investigative Site, Calgary, Alberta, Canada
Novartis Investigative Site, Edmonton, Alberta, Canada
Novartis Investigative Site, Vancouver, British Columbia, Canada
Novartis Investigative Site, Victoria, British Columbia, Canada
Novartis Investigative Site, Toronto, Ontario, Canada
Novartis Investigative Site, Toronto, Ontario, Canada
Novartis Investigative Site, Greenfield Park, Quebec, Canada
Novartis Investigative Site, Montreal, Quebec, Canada
Novartis Investigative Site, Saskatoon, Saskatchewan, Canada
Novartis Investigative Site, Herlev, , Denmark
Novartis Investigative Site, Angers cedex 02, , France
Novartis Investigative Site, Lille Cedex, , France
Novartis Investigative Site, Paris, , France
Novartis Investigative Site, Vandoeuvre-Les-Nancy Cede, , France
Novartis Investigative Site, Aschaffenburg, , Germany
Novartis Investigative Site, Berlin, , Germany
Novartis Investigative Site, Weiden, , Germany
Novartis Investigative Site, Hongkong, , Hong Kong
Novartis Investigative Site, Shatin, New Territories, , Hong Kong
Novartis Investigative Site, Arezzo, AR, Italy
Novartis Investigative Site, Modena, MO, Italy
Novartis Investigative Site, Napoli, , Italy
Novartis Investigative Site, Seoul, Korea, Korea, Republic of
Novartis Investigative Site, Seoul, Korea, Korea, Republic of
Novartis Investigative Site, Seoul, Korea, Korea, Republic of
Novartis Investigative Site, Daejeon, , Korea, Republic of
Novartis Investigative Site, Chihuahua, , Mexico
Novartis Investigative Site, Den Haag, , Netherlands
Novartis Investigative Site, Maastricht, , Netherlands
Novartis Investigative Site, Jesus Maria, Lima, Peru
Novartis Investigative Site, Elche, Alicante, Spain
Novartis Investigative Site, Sevilla, Andalucia, Spain
Novartis Investigative Site, Sabadell, Barcelona, Spain
Novartis Investigative Site, Lleida, Cataluna, Spain
Novartis Investigative Site, Taipei, Taiwan, ROC, Taiwan
Novartis Investigative Site, Niaosong Township, , Taiwan
Novartis Investigative Site, Bangkok, , Thailand
Novartis Investigative Site, Istanbul, , Turkey
Novartis Investigative Site, Bristol, Avon, United Kingdom
Novartis Investigative Site, London, , United Kingdom
Novartis Investigative Site, Nottingham, , United Kingdom
Contact Details
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR
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