Spots Global Cancer Trial Database for Study Comparing Bevacizumab + Temsirolimus vs. Bevacizumab + Interferon-Alfa In Advanced Renal Cell Carcinoma Subjects
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Trial Identification
Brief Title: Study Comparing Bevacizumab + Temsirolimus vs. Bevacizumab + Interferon-Alfa In Advanced Renal Cell Carcinoma Subjects
Official Title: Phase 3b, Randomized, Open-Label Study Of Bevacizumab + Temsirolimus Vs. Bevacizumab + Interferon-Alfa As First-Line Treatment In Subjects With Advanced Renal Cell Carcinoma
Study ID: NCT00631371
Conditions
Study Description
Brief Summary: Primary objective: Comparison of independently assessed progression free survival (PFS) in subjects administered Bevacizumab + Temsirolimus vs. those administered Bevacizumab + Interferon-Alfa. Secondary objectives: safety, Investigator assessed PFS, objective response rate (independently assessed), and overall survival.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Hematology Oncology Services of Arkansas, Little Rock, Arkansas, United States
South County Hematology/Oncology, Chula Vista, California, United States
Cancer Center Oncology Medical Group, La Mesa, California, United States
UCLA Medical Center, Los Angeles, California, United States
UCLA, Los Angeles, California, United States
UCLA, Los Angeles, California, United States
North County Oncology Medical Clinic, Oceanside, California, United States
Medical Oncology Associates - SD, San Diego, California, United States
Sharp Memorial Hospital Investigational Pharmacy, San Diego, California, United States
Sharp Rees-Stealy, San Diego, California, United States
California Pacific Medical Center, San Francisco, California, United States
Pacific Hematology/Oncology Associates, San Francisco, California, United States
San Francisco Oncology Associates, San francisco, California, United States
Cohen & Hufford MD's INC, San Francisco, California, United States
The Jones Clinic, PC, New Albany, Mississippi, United States
The Cleveland Clinic, Cleveland, Ohio, United States
Edmond Oncology Center, Edmond, Oklahoma, United States
OU Medical Center, Oklahoma City, Oklahoma, United States
OU Physician's Building, Oklahoma City, Oklahoma, United States
University of Oklahoma, Oklahoma City, Oklahoma, United States
The Jones Clinic, PC, Germantown, Tennessee, United States
The Vanderbilt Clinic, Nashville, Tennessee, United States
University of Washington Medical Center, Seattle, Washington, United States
Virginia Mason Medical Center, Seattle, Washington, United States
Seattle Cancer Care Alliance, Seattle, Washington, United States
Centro Oncológico Rosario, Rosario, Santa Fé, Argentina
Centro Medico San Roque, San Miguel de Tucuman, Tucuman, Argentina
ISIS Clinica Especializado, Santa Fe, , Argentina
Mater Adult Hospital, South Brisbane, Queensland, Australia
Royal Adelaide Hospital, Adelaide, South Australia, Australia
Ashford Cancer Center Research, Kurralta Park, South Australia, Australia
Cancer Care SA, Kurralta Park, , Australia
Mater Private Hospital, South Brisbane, , Australia
ZNA Middelheim, Antwerpen, , Belgium
Universitair Ziekenhuis Gent, Gent, , Belgium
Jessa Ziekenhuis - campus Virga Jessa, Hasselt, , Belgium
Cliniques Universitaires de Mont-Godinne UCL, Mont-Godinne, , Belgium
Centro Goiano de Oncologia, Goiania, GO, Brazil
Centro Goiano de Oncologia - CGO, Goiania, GO, Brazil
ProCura - Centro Goiano de Pesquisa Clínica Ltda, Goiania, GO, Brazil
Clínica de Oncologia de Porto Alegre Sociedade Simples Ltda, Porto Alegre, Rio Grande do Sul, Brazil
Instituto Nacional de Cancer - INCA, Rio de Janeiro, RJ, Brazil
Associaçao Hospital de Caridade Ijui, Ijui, RS, Brazil
Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil
Clinica de Oncologia de Porto Alegre - Sociedade Simples Ltda., Porto Alegre, RS, Brazil
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, Sao Paulo, Brazil
Instituto de Oncologia de Piracicaba S/S Ltda, Piracicaba, SP, Brazil
Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira - ICESP, Sao Paulo, SP, Brazil
Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, , Brazil
Instituto Nacional do Cancer - INCA, Rio de Janeiro, , Brazil
Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Centre de Sante et de Services Sociaux de Rimouski - Neigette, Rimouski, Quebec, Canada
Instituto Nacional del Cancer, Santiago, Region Metropolitana / Chile, Chile
Fundacion Arturo Lopez Perez, Santiago, , Chile
Instituto Clinico Oncologico del Sur, Santiago, , Chile
Oncologos del Occidente S.A, Pereira, Risaralda, Colombia
Oblastni nemocnice Jicin a s, Jicin, Ceska republika, Czech Republic
Masarykuv onkologicky ustav, Brno, , Czech Republic
Fakultni nemocnice Olomouc, Olomouc, , Czech Republic
Krajska zdravotni, a.s., Usti nad Labem, , Czech Republic
Centre Jean Perrin, Clermont-Ferrand, , France
Clinique Sainte Marguerite, Hyères, , France
Hopital Andre Mignot, Le Chesnay, , France
Centre médical Oncogard, Nimes, , France
CHU de Poitiers, Poitiers Cedex, , France
CHU de Rouen, Rouen Cedex, , France
Centre rené Gauducheau, Saint-Herblain-Nantes, , France
Hopital Foch, Suresnes, , France
Institut Gustave Roussy, Villejuif Cedex, , France
Vivantes Klinikum am Urban, Neztwerk fuer Gesundheit GmbH, Berlin, , Germany
Universitaetsklinikum Hamburg Eppendorf, Hamburg, , Germany
Klinikum Region Hannover, Krankenhaus Siloah, Hannover, , Germany
TU Muenchen, rechts der Isar, Muenchen, , Germany
Pamela Youde Nethersole Eastern Hospital, Chai Wan, , Hong Kong
Prince of Wales Hospital, Hong Kong, , Hong Kong
Queen Mary Hospital, Hong Kong, , Hong Kong
Orszagos Onkologiai Intezet, Budapest, , Hungary
Uzsoki Utcai Korhaz, Budapest, , Hungary
Petz Aladar Megyei Oktato Korhaz, Gyor, , Hungary
Josa Andras Oktato Korhaz Nonprofit Kft., Nyiregyhaza, , Hungary
Szegedi Tudomanyegyetem, Urologiai Klinika, Szeged, , Hungary
Veszprem Megyei Csolnoky Ferenc, Veszprem, , Hungary
Vedanta Institute of Medical Sciences, Ahmedabad, Gujarat, India
Healthcare Global Enterprises Limited, Bangalore, Karnataka, India
Lakeshore Hospital & Research Center Limited, Kochi, Kerala, India
Jawaharlal Nehru Cancer Hospital, Department of Medical Oncology, Bhopal, Madhya Pradesh, India
Tata Memorial Center, Mumbai, Maharashtra, India
Tata Memorial Centre, Navi Mumbai, Maharashtra, India
Jehangir Hospital, Pune, Maharashtra, India
Searoc Cancer Centre, Jaipur, Rajasthan, India
Apollo Hospital, Chennai, Tamil Nadu, India
Regional Cancer Centre, Kerela, Trivandrum, India
Divisione di Urologia, Azienda Ospedaliera Policlinico Consorziale di Bari, Bari, , Italy
Sezione di Oncologia Medica Centro di Ricerca Clinica, Chieti, , Italy
Unità Operativa di Oncologia, Azienda Ospedaliera Policlinico di Modena, Modena, , Italy
Farmacia del Comitato Etico Provinciale di Modena, Modena, , Italy
Struttura Complessa di Oncologia Medica Ospedale Santa Maria della Misericordia, Perugia, , Italy
IFO- Istituti Fisioterapici Ospitalieri, Roma, , Italy
Azienda Ospedaliera S. Maria, Terni, , Italy
Samsung Medical Center, Seoul, Korea, Korea, Republic of
Yonsei University Health System-Severance Hospital, Seoul, , Korea, Republic of
University Malaya Medical Centre, Kuala Lumpur, , Malaysia
Hospital Aranda de la Parra, Leon, Guanajuato, Mexico
Spaarne Ziekenhuis, Hoofddorp, , Netherlands
Uniwersyteckie Centrum Kliniczne, Gdansk, , Poland
Szpital Specjalistyczny im. L. Rydygiera Sp. z o.o., Krakow, , Poland
Centrum Onkologii Ziemi Lubelskiej im. sw Jana z Dukli, Lublin, , Poland
Szpital Kliniczny Przemienienia Panskiego UM im. Karola Marcinkowskiego w Poznaniu, Poznan, , Poland
Centrum Onkologii, Instytut im. M. Sklodowskiej-Curie, Warszawa, , Poland
Centrum Medyczne Ostrobramska NZOZ "Magodent", Warszawa, , Poland
Wojskowy Instytut Medyczny, Pracownia Badan Cynnosciowych Ukladu Oddechowego, Klinika Chorob Wewnetr, Warszawa, , Poland
Wojskowy Intsytut Medyczny, Zaklad Diagnostyki Laboratoryjnej CSK MON, Warszawa, , Poland
Wojskowy Intsytut Medyczny, Zaklad Medycyny Nuklearnej CSK MON, Warszawa, , Poland
Hospital de San Joao, Porto, , Portugal
Hospital de São João, Porto, , Portugal
Medical Radiology Research Center of the Minzdravsotsrazvitiya of Russia, Obninsk, Kaluga region, Russian Federation
Leningrad Regional Oncology Dispensary, Saint-Petersburg, Leningradskaya oblast, Russian Federation
Republican Clinical Oncology Dispensary of Minzdrav of Tatarstan Republic, Kazan, , Russian Federation
Chair of Radiology and Radiotherapy, Moscow, , Russian Federation
N.N. Blokhin Russian Cancer Research Center, Department of Clinical Pharmacology and Chemotherapy, Moscow, , Russian Federation
N.N. Blokhin Russian Cancer Research Center, Department of Urology, Moscow, , Russian Federation
Moscow Scientific Research Oncology Institute P.A. Herzen, Moscow, , Russian Federation
Privolzhskiy District Medical Center of Federal Biomedical Agency, Nizhni Novgorod, , Russian Federation
Scientific research Institute of Oncology N.N. Petrov, Pesochny, Saint-Petersburg, , Russian Federation
City Hospital No.26, Saint-Petersburg, , Russian Federation
City Pokrovskaya Hospital, Saint-Petersburg, , Russian Federation
Clinical Center of Serbia, Belgrade, , Serbia
Institute for Oncology and Radiology of Serbia, Belgrade, , Serbia
Military Medical Academy, Belgrade, , Serbia
National Cancer Centre Singapore, Singapore, , Singapore
Fakultna Nemocnica s poliklinikou F D Roosevelta, Banska Bystrica, , Slovakia
Oddelenie funkcnej diagnostiky, Banska Bystrica, , Slovakia
Klinika pneumologie a ftiziologie FNsP LFUK, Bratislava, , Slovakia
Fakultna Nemocnica s poliklinikou akad L Derera, Bratislava, , Slovakia
Klinica nuklcarncj mediciny, Martin, , Slovakia
Klinika nuklearnej mediciny JLF UK a Martinskej fakultnej nemocnice, Martin, , Slovakia
Klinika tuberkulozy a plucnych chorob UK JLF a Martinskej fakultnej nemocince, Martin, , Slovakia
Nemocnica s poliklinikou Skalica, Skalica, , Slovakia
KK MED, s.r.o., Zilina, , Slovakia
MEDIVASA s.r.o., Zilina, , Slovakia
Nemocnica s poliklinikou Zilina, Zilina, , Slovakia
GVI Oncology Trial Unit, Kraaifontein, Cape Town, South Africa
Westridge Medical Centre, Mayville, Durban, South Africa
Pretoria Urology Hospital, Hatfield, Pretoria, South Africa
Panorama Medical Centre, Panorama, Cape Town, Western Cape, South Africa
University of the Witwatersrand Oncology, Parktown, , South Africa
Langenhoven Drive Oncology Centre, Port Elizabeth, , South Africa
Dr. Fourie & Voges, Pretoria, , South Africa
Institut Catala Doncologia, L'hospitalet de Llobregat, Barcelona, Spain
Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain
Hospital Sant Creu I Sant Pau, Barcelona, , Spain
Hospital del mar de Barcelona, Barcelona, , Spain
Hospital de Madrid Norte-Sanchinarro, Madrid, , Spain
Instituto Valenciano de Oncología, Valencia, , Spain
Veterans General Hospital-Taipei, Taipei, ROC, Taiwan
Tri-Service General Hospital, Neihu, Tapei, Taiwan
China Medical University Hospital, Taichung, , Taiwan
National Taiwan University Hospital, Taipei TOC, , Taiwan
Division of Oncology, Tao Yuan, , Taiwan
Universitet, kafedra onkologyy, Chenivtsi, , Ukraine
A.P Romodanov Itstitut nejrohirurhii, Chernovtsi, , Ukraine
Uchbobo-naukovyi likuvalnyi kompleks DDMU im. M.Gor'kogo, Donetsk, , Ukraine
Donetskyy Oblasyy protypukhlynnyy Tsenter, Donetsk, , Ukraine
Donetske Obl. clinico-teritorial'ne medichne ob'yednannya, Donetsk, , Ukraine
"State Institution ""Institute for Occupational Health of the, Kiev, , Ukraine
R.E.Kavetsky Institute of experimental pathology, oncology and radiobiology NAS of Ukraine,Laborator, Kiev, , Ukraine
A.P Romodanov Itstitut nejrohirurhii, Kiyv, , Ukraine
Oblasnyy onkologychnyy dispanser, onkourologichne viddilennya, Ivano-Frankivskiy Derzhavniy Medichni, Medychna vul., Ivano-Frankivsk, , Ukraine
Southampton General Hospital, Southampton, Hampshire, United Kingdom
Christie Hospital, Withington, Manchester, United Kingdom
University of Leeds, Leeds, North Yorkshire, United Kingdom
Guy's Hospital, London, , United Kingdom
Contact Details
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR
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