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Spots Global Cancer Trial Database for Intra-arterial Chemotherapy for Children With Retinoblastoma

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Trial Identification

Brief Title: Intra-arterial Chemotherapy for Children With Retinoblastoma

Official Title: Phase 1-2 Study of Injection of Melphalan Into the Ophthalmic Artery in Children With Retinoblastoma

Study ID: NCT00906113

Conditions

Retinoblastoma

Study Description

Brief Summary: Retinoblastoma is a cancer of the eye that occurs exclusively in children. The treatment for retinoblastoma may include surgery, chemotherapy, radiation and local treatments to the eye such as freezing (cryotherapy) and local radiation (brachytherapy). In some cases, a child with retinoblastoma will have active cancer in a single remaining eye with useful vision. In such cases, it is sometimes necessary to remove this eye. In such cases, the injection of chemotherapy directly into the artery that supplies the eye and the tumor may lead to regression of the tumor without the need to remove the eye. This form of treatment was pioneered by a group in New York (Abramson et al). In this study the investigators will assess the efficacy and safety of the technique in a group of children with retinoblastoma.

Detailed Description:

Eligibility

Minimum Age: 6 Months

Eligible Ages: CHILD

Sex: ALL

Healthy Volunteers: No

Locations

Hadassah University Hospital, Jerusalem, , Israel

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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