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Brief Title: Carboplatin Periocular Injection for Retinoblastoma
Official Title: Carboplatin Periocular Injection in the Treatment for Retinoblastoma--A Single Center, Randomized Study to Evaluate the Efficacy of Carboplatin in Subjects With Retinoblastoma
Study ID: NCT02137928
Brief Summary: This study will evaluate the clinical efficacy of periocular injections of carboplatin together with chemotherapy in the treatment of Retinoblastoma as compared to chemotherapy alone.
Detailed Description: This study will be a phase Ⅲ open label interventional case series. Patients with retinoblastoma will be randomized to receive chemotherapy with or without periocular injections of carboplatin at a dose of 20mg/2 ml. Patients will receive carboplatin periocular on a monthly basis for a total duration of therapy of 6 months. Patients will be followed for 24 months .
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China
Name: Huasheng Yang, Doctor
Affiliation: Zhongshan Ophthalmic Center, Sun Yat-sen University
Role: STUDY_CHAIR