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Brief Title: Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009)
Official Title: Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated
Study ID: NCT02870907
Brief Summary: Postoperative Treatment of Unilateral Retinoblastoma After Primary Enucleation according to histopathological risk factors of the International Retinoblastoma Staging Working Group.
Detailed Description: Post operative chemotherapy +/- radiotherapy according to histopathological risk factors of the International Retinoblastoma Staging Working Group. * Low risk group : * No optic nerve involvement. * Intra and prelaminar involvement * No choroidal involvement. * Minimal superficial choroidal involvement . * Intermediate risk group, 2 sub groups : * Sub group 1 : * Retrolaminar involvement without Invasion of surgical margin associated or not to massive choroidal involvement * Anterior segment involvement. * Intrascleral involvement. * Sub Group 2 : * Isolated massive choroidal involvement. * High risk group : * Invasion of the surgical margin of the optic nerve * and/or microscopic extrascleral involvement * Optic nerve meningeal sheat involvement .
Minimum Age: 2 Months
Eligible Ages: CHILD
Sex: ALL
Healthy Volunteers: No
Chr Felix Guyon, Saint-Denis, La Réunion, France
Hopital Nord Chu Amiens, Amiens, , France
Chu Angers, Angers, , France
Hopital Jean Minioz, Besancon, , France
Chu R; Pellegrin, Bordeaux, , France
Chu Morvan, Brest, , France
CHU CAEN, Caen, , France
Chu Estaing, Clermont Ferrand, , France
Chu Bocage, Dijon, , France
Chu de Grenoble, Grenoble, , France
Centre Oscar Lambret, Lille, , France
Chu Limoges, Limoges, , France
Centre Leon Berard, Lyon, , France
Hopital D'Enfants La Timone, Marseille, , France
Hopital Arnaud de Villeneuve, Montpellier, , France
Chu Nantes, Nantes, , France
Chu de Nice, Nice, , France
Institut Curie, Paris, , France
Chu de Poitiers, Poitiers, , France
Chur de Reims, Reims, , France
Chu de Rennes, Rennes, , France
Chu de Rouen, Rouen, , France
Chu Saint Etienne, Saint Etienne, , France
Hoptial Hautepierre, Strasbourg, , France
Chu Toulouse, Toulouse, , France
Chu Tours, Tours, , France
Chu Nancy, Vandoeuvre Les Nancy, , France