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Brief Title: Physiologic MR Imaging of Salivary Gland Tumors
Official Title: Physiologic MR Imaging in Distinguishing Benign From Malignant Salivary Gland Tumors
Study ID: NCT04452162
Brief Summary: The goal of this study is to use advanced Magnetic Resonance Imaging (MRI) techniques to help identify the difference between cancerous and non-cancerous salivary gland tumors for improving treatment strategies and to aid in the prediction of disease progression.
Detailed Description: The goal of this proposed study is to investigate the potential utility of combined analysis of parameters (Ktrans, ti and ADC) in discriminating benign from malignant salivary glands tumors (SGTs). A total of 30 treatment naïve patients suspicious of SGT as observed on clinical evaluation and prior routine CT, MRI, Ultrasound, FNAC and/or PET will undergo 3T MRI. The MRI protocol will include acquisition of anatomical images with and without contrast agent injection, diffusion imaging and dynamic contrast enhanced-MRI.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Name: Sanjeev Chawla
Affiliation: Professor
Role: PRINCIPAL_INVESTIGATOR