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Brief Title: GENSARC 2008 : Medical Economic Evaluation of the Molecular Detection by FISH (Fluorescent in Situ Hybridization) and by PCR (Polymerase Chain Reaction) of Sarcomas Specific Translocations and Amplifications .
Official Title: GENSARC 2008 : Medical Economic Evaluation of the Molecular Detection by FISH (Fluorescent in Situ Hybridization) and by PCR (Polymerase Chain Reaction) of Sarcomas Specific Translocations and Amplifications .
Study ID: NCT00847691
Brief Summary: The clinical and histological diagnosis of sarcomas is often very difficult. The identification of chromosomal and molecular anomalies, such as amplifications, deletions or fusion genes is a powerful help for establishing a correct diagnosis of sarcomas and their benign counterparts. However, the cost of the cytogenetic and molecular techniques for the detection of these alterations is often a limitation to their use. The aim of our study is to evaluate the direct cost of the molecular techniques in comparison to the cost that would be generated by an appropriate therapy and care management of the patient in case of an erroneous diagnosis.
Detailed Description:
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Departement de Pathologie de l'Institut Bergonié, Bordeaux, , France
Laboratoire de Biochimie et Biologie Moléculaire, CHRU de Lille, Lille, , France
Département d'Anantomie et de Cytologie Pathologie, Centre Léon Berard, Lyon, , France
Laboratoire de Génétique des Tumeurs Solides, Nice, , France
Institut Curie, Paris Cedex 5, , France
Service d'Anatomo-Pathologie, Centre Paul Strauss, Strasbourg, , France
Unité de Biologie Moléculaire, CHU de Hautepierre, Strasbourg, , France
Département de biologie et de pathologie médicales, Institut Gustave roussy, Villejuif, , France
Name: Florence PEDEUTOUR, PhD
Affiliation: Laboratoire de Génétique des Tumeurs Solides
Role: PRINCIPAL_INVESTIGATOR