Spots Global Cancer Trial Database for Application of Magnetic Resonance Fat-Free Imaging

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Trial Identification

Brief Title: Application of Magnetic Resonance Fat-Free Imaging

Official Title: Application of Magnetic Resonance Fat-Free Imaging

Study ID: NCT00944476

Conditions

Sarcoma

Interventions

Fat-free MRI images utilizing standard magnetization, Questionnaire before the MRI exam

Study Description

Brief Summary: Magnetic resonance imaging (MRI) is presently the best study for assessing the size and extent of the patient's sarcoma. Many sarcomas contain fat that can interfere with the accuracy of sarcoma detection. The investigators have developed a new MRI method that can suppress all the fat signals in the patient's tumor and this may improve the investigators' ability to see the patient's sarcoma. The purpose of this study is to determine if the investigators' new fat-free imaging methods provides them with images that are better than, equal to, or worse than those images obtained by standard MRI methods. This study may help the investigators develop a more accurate MRI examination.

Detailed Description: In addition, we will perform the same scans on 4 volunteers who have no history of sarcoma. Scanning volunteers will allow us to optimize the imaging technique by 1.) Determine the best combination of pulse-sequence and magnetization transfer technique to obtain the greatest contrast and 2.) Determine the parameters of repetition time (TR), echo time (TE) and magnetization transfer time and power in order to reduce overall image acquisition time while optimizing image quality. Honing this technique on volunteers will allow us to decrease scan time and potential discomfort for patients.