Spots Global Cancer Trial Database for Biomarkers in Samples From Young Patients With Soft Tissue Sarcoma
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Trial Identification
Brief Title: Biomarkers in Samples From Young Patients With Soft Tissue Sarcoma
Official Title: Next Generation Sequencing of Childhood Soft Tissue Sarcomas to Identify Drivers of Primary and Metastatic Disease
Study ID: NCT01342783
Conditions
Study Description
Brief Summary: RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This research trial is studying biomarkers in samples from young patients with soft tissue sarcoma.
Detailed Description: OBJECTIVES: * To identify the key components of driver pathways of primary and secondary soft tissue sarcomas. * To perform the next-generation sequencing on primary versus normal on undifferentiated sarcomas. OUTLINE: Genomic DNA and RNA samples from undifferentiated sarcoma tumors are analyzed by next-generation sequencing for somatic mutations. Normal matched lymphocytes and tissue are also analyzed.
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Contact Details
Name: Poul Sorensen, MD, PhD
Affiliation: British Columbia Cancer Agency
Role: PRINCIPAL_INVESTIGATOR
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