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Spots Global Cancer Trial Database for The Sarcoma Biology and Outcome Project

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Trial Identification

Brief Title: The Sarcoma Biology and Outcome Project

Official Title: A Prospective Registry Study on Biological Disease Profile, Intervention Type and Clinical Outcome in Adolescent and Adult Patients With Soft-tissue and Bone Sarcoma

Study ID: NCT04758325

Interventions

Study Description

Brief Summary: SarcBOP - An interdisciplinary and translational registry SarcBOP aims to establish a database that integrates every aspect possibly relevant to sarcoma treatment and research. SarcBOP thus will not be limited to specific questions or patient groups, but instead will build a comprehensive database including clinical, pathologic, and radiologic information, multi-layered molecular data, and patient-reported outcomes, combined with a dedicated biobank for tissue samples and liquid biopsies. As the study integrates seamlessly with the clinical activities of the Heidelberg Sarcoma Center, the Molecular Diagnostics Program of NCT Heidelberg, including the NCT/DKTK MASTER Program, and with the NCT Trial Center, including the PMO Clinical Trials Program, SarcBOP will generate a comprehensive and continuously growing resource for clinicians, researchers, and, finally, patients.

Detailed Description: The following data are collected and stored: * Demographics * Comorbidities * Clinical characteristics at diagnosis, relapse and progression * Radiologic images * Histological images * Treatments including DRG and OPS data, including detailed information on surgical, radiation, and medical therapy as well as treatment relevant follow-up data * Longitudinal disease assessments * Clinical outcome * Genomic, transcriptomic, epigenomic and proteomic data * Patient reported outcomes Furthermore, biological samples are collected and processed by the Sample Processing Laboratory of the Heidelberg Center for Personalized Oncology and the NCT Biobank.

Eligibility

Minimum Age: 12 Years

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

National Center for Tumour Diseases, University Hospital Heidelberg, Heidelberg, Baden-Württemberg, Germany

Contact Details

Name: Richard F. Schlenk, Prof.Dr.med

Affiliation: National Center for Tumour Disease

Role: PRINCIPAL_INVESTIGATOR

Name: Christoph E. Heilig, Dr. med.

Affiliation: National Center for Tumour Disease

Role: STUDY_DIRECTOR

Name: Stefan Fröhling, Prof. Dr.

Affiliation: National Center for Tumour Disease

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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