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Spots Global Cancer Trial Database for Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma

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Trial Identification

Brief Title: Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma

Official Title: Phase II Multi-Center Trial of Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma

Study ID: NCT04076579

Interventions

Olaparib
Trabectedin

Study Description

Brief Summary: This phase II trial studies how well trabectedin and olaparib work in treating patients with sarcoma that cannot be removed by surgery or has spread to other places in the body. Drugs used in chemotherapy, such as trabectedin, work in different ways to stop the growth of tumor cells, either by killing cells, stopping them from dividing or stopping them from spreading. Olaparib may stop the growth of tumor cells by blocking pathways responsible for repairing damaged cells. Giving trabectedin and olaparib may shrink or stop the tumor from growing.

Detailed Description:

Keywords

Eligibility

Minimum Age: 16 Years

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States

Contact Details

Name: Rashmi Chugh, M.D.

Affiliation: University of Michigan Rogel Cancer Center

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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