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Brief Title: A Study of PM8002 in Combination With Chemotherapy in Patients With SCLC
Official Title: A Phase II Study to Evaluate Efficacy, Safety and Pharmacokinetics of PM8002 Injection in Combination With Paclitaxel Injection as Second Line Treatment for Small Cell Lung Cancer(SCLC)
Study ID: NCT05879068
Brief Summary: PM8002 is a bispecific antibody targeting PD-L1 and VEGF. This study will evaluate the efficacy and safety of PM8002 in combination with paclitaxel as second line treatment for SCLC.
Detailed Description: This is a phase II, single arm study assessing the efficacy and safety of PM8002 in combination with paclitaxel as second line treatment for SCLC who failed first-line platinum-based chemotherapy with or without checkpoint inhibitors therapy
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Jilin Provincial Tumor Hospital, Changchun, , China
Name: Ying Cheng
Affiliation: Jilin Provincial Tumor Hospital
Role: PRINCIPAL_INVESTIGATOR