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Spots Global Cancer Trial Database for Hepatic Vein-sparing Hepatectomy for Colorectal Liver Metastases at the Caval Confluence

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Trial Identification

Brief Title: Hepatic Vein-sparing Hepatectomy for Colorectal Liver Metastases at the Caval Confluence

Official Title: Hepatic Vein-sparing Hepatectomy for Colorectal Liver Metastases at the Caval Confluence: Validation on Intention-to-treat Analysis of a IOUS-guided Approach

Study ID: NCT02391207

Study Description

Brief Summary: Major hepatectomies are generally selected for tumors involving the hepatic vein (HV) at the caval confluence (CC). As alternative, HV reconstruction has been proposed. The present study aimed to evaluate the feasibility and safety of a HV-sparing policy guided by intraoperative ultrasonography (IOUS) in a cohort of patients having at least one colorectal liver metastasis (CLM) in contact with a HV at CC. HV section can be avoided in the large majority of cases thanking to CLMs detachment or to HV partial resection or reconstruction: this policy seems feasible, safe, reduces the need of major hepatectomies, and oncologically provides an adequate local control.

Detailed Description:

Keywords

Eligibility

Minimum Age: 28 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Department of Hepatobiliary and General Surgery, Humanitas Research Hospital, University of Milan, Rozzano, Milan, Italy

Contact Details

Name: Guido Torzilli, MD,PhD,FACS

Affiliation: Department of Hepatobiliary and General Surgery, University of Milan, Humanitas Research Hospital, Rozzano, Milan, Italy

Role: STUDY_DIRECTOR

Name: Fabio Procopio, MD

Affiliation: Department of Hepatobiliary and General Surgery, University of Milan, Humanitas Research Hospital, Rozzano, Milan, Italy

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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