Spots Global Cancer Trial Database for Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)
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Trial Identification
Brief Title: Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)
Official Title: A Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled Variable Treatment Duration Study Evaluating the Efficacy and Safety of Siponimod (BAF312) in Patients With Secondary Progressive Multiple Sclerosis Followed by Extended Treatment With Open-label BAF312.
Study ID: NCT01665144
Conditions
Study Description
Brief Summary: Evaluate the safety and efficacy of Siponimod (BAF312) versus placebo in a variable treatment duration in patients with secondary progressive multiple sclerosis (Core Part) followed by extended treatment with open-label BAF312 to obtain data on long-term safety, tolerability and efficacy (Extension Part).
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Novartis Investigative Site, Phoenix, Arizona, United States
Novartis Investigative Site, Berkeley, California, United States
Novartis Investigative Site, Los Angeles, California, United States
Novartis Investigative Site, Oceanside, California, United States
Novartis Investigative Site, Sacramento, California, United States
Novartis Investigative Site, Aurora, Colorado, United States
Novartis Investigative Site, Basalt, Colorado, United States
Novartis Investigative Site, Boulder, Colorado, United States
Novartis Investigative Site, Colorado Springs, Colorado, United States
Novartis Investigative Site, Englewood, Colorado, United States
Novartis Investigative Site, Fairfield, Connecticut, United States
Novartis Investigative Site, Delray Beach, Florida, United States
Novartis Investigative Site, Jacksonville, Florida, United States
Novartis Investigative Site, Maitland, Florida, United States
Novartis Investigative Site, Ormond Beach, Florida, United States
Novartis Investigative Site, Port Charlotte, Florida, United States
Novartis Investigative Site, Sunrise, Florida, United States
Novartis Investigative Site, Tampa, Florida, United States
Novartis Investigative Site, Tampa, Florida, United States
Novartis Investigative Site, Vero Beach, Florida, United States
Novartis Investigative Site, Chicago, Illinois, United States
Novartis Investigative Site, Evanston, Illinois, United States
Novartis Investigative Site, Flossmoor, Illinois, United States
Novartis Investigative Site, Baltimore, Maryland, United States
Novartis Investigative Site, Ann Arbor, Michigan, United States
Novartis Investigative Site, Detroit, Michigan, United States
Novartis Investigative Site, Detroit, Michigan, United States
Novartis Investigative Site, Plymouth, Minnesota, United States
Novartis Investigative Site, Saint Louis, Missouri, United States
Novartis Investigative Site, Las Vegas, Nevada, United States
Novartis Investigative Site, Lebanon, New Hampshire, United States
Novartis Investigative Site, Freehold, New Jersey, United States
Novartis Investigative Site, Albuquerque, New Mexico, United States
Novartis Investigative Site, New York, New York, United States
Novartis Investigative Site, New York, New York, United States
Novartis Investigative Site, Patchogue, New York, United States
Novartis Investigative Site, Stony Brook, New York, United States
Novartis Investigative Site, Charlotte, North Carolina, United States
Novartis Investigative Site, Akron, Ohio, United States
Novartis Investigative Site, Dayton, Ohio, United States
Novartis Investigative Site, Portland, Oregon, United States
Novartis Investigative Site, Springfield, Oregon, United States
Novartis Investigative Site, Philadelphia, Pennsylvania, United States
Novartis Investigative Site, Providence, Rhode Island, United States
Novartis Investigative Site, Dallas, Texas, United States
Novartis Investigative Site, Lubbock, Texas, United States
Novartis Investigative Site, San Antonio, Texas, United States
Novartis Investigative Site, Burlington, Vermont, United States
Novartis Investigative Site, Seattle, Washington, United States
Novartis Investigative Site, Seattle, Washington, United States
Novartis Investigative Site, Milwaukee, Wisconsin, United States
Novartis Investigative Site, Caba, Buenos Aires, Argentina
Novartis Investigative Site, Caba, Buenos Aires, Argentina
Novartis Investigative Site, Caba, Buenos Aires, Argentina
Novartis Investigative Site, Capital Federal, Buenos Aires, Argentina
Novartis Investigative Site, Buenos Aires, , Argentina
Novartis Investigative Site, Cordoba, , Argentina
Novartis Investigative Site, Camperdown, New South Wales, Australia
Novartis Investigative Site, Kogarah, New South Wales, Australia
Novartis Investigative Site, Liverpool, New South Wales, Australia
Novartis Investigative Site, Heidelberg, Victoria, Australia
Novartis Investigative Site, Parkville, Victoria, Australia
Novartis Investigative Site, Klagenfurt, , Austria
Novartis Investigative Site, Vienna, , Austria
Novartis Investigative Site, Wien, , Austria
Novartis Investigative Site, Edegem, Antwerpen, Belgium
Novartis Investigative Site, Brugge, , Belgium
Novartis Investigative Site, Bruxelles, , Belgium
Novartis Investigative Site, Fraiture En Condroz, , Belgium
Novartis Investigative Site, Gent, , Belgium
Novartis Investigative Site, Leuven, , Belgium
Novartis Investigative Site, Pelt, , Belgium
Novartis Investigative Site, Sijsele, , Belgium
Novartis Investigative Site, Sofia, , Bulgaria
Novartis Investigative Site, Sofia, , Bulgaria
Novartis Investigative Site, Sofia, , Bulgaria
Novartis Investigative Site, Varna, , Bulgaria
Novartis Investigative Site, Calgary, Alberta, Canada
Novartis Investigative Site, Edmonton, Alberta, Canada
Novartis Investigative Site, Burnaby, British Columbia, Canada
Novartis Investigative Site, Halifax, Nova Scotia, Canada
Novartis Investigative Site, Kingston, Ontario, Canada
Novartis Investigative Site, Ottawa, Ontario, Canada
Novartis Investigative Site, Toronto, Ontario, Canada
Novartis Investigative Site, Greenfield Park, Quebec, Canada
Novartis Investigative Site, Montreal, Quebec, Canada
Novartis Investigative Site, Montreal, Quebec, Canada
Novartis Investigative Site, Beijing, Beijing, China
Novartis Investigative Site, Beijing, Beijing, China
Novartis Investigative Site, Changchun, Jilin, China
Novartis Investigative Site, Taiyuan, Shanxi, China
Novartis Investigative Site, XI An, Shanxi, China
Novartis Investigative Site, Chengdu, Sichuan, China
Novartis Investigative Site, Beijing, , China
Novartis Investigative Site, Beijing, , China
Novartis Investigative Site, Shanghai, , China
Novartis Investigative Site, Brno, Czech Rep., Czechia
Novartis Investigative Site, Teplice, Czech Republic, Czechia
Novartis Investigative Site, JIhlava, , Czechia
Novartis Investigative Site, Prague 5, , Czechia
Novartis Investigative Site, Praha, , Czechia
Novartis Investigative Site, Tallinn, , Estonia
Novartis Investigative Site, Tallinn, , Estonia
Novartis Investigative Site, Nancy, Cedex, France
Novartis Investigative Site, Bordeaux Cedex, , France
Novartis Investigative Site, Caen, , France
Novartis Investigative Site, Lille, , France
Novartis Investigative Site, Marseille Cedex 05, , France
Novartis Investigative Site, Montpellier, , France
Novartis Investigative Site, Nimes, , France
Novartis Investigative Site, Paris 13, , France
Novartis Investigative Site, Rennes, , France
Novartis Investigative Site, St Herblain, , France
Novartis Investigative Site, Strasbourg, , France
Novartis Investigative Site, Regensburg, Bavaria, Germany
Novartis Investigative Site, Aschaffenburg, , Germany
Novartis Investigative Site, Bad Mergentheim, , Germany
Novartis Investigative Site, Bayreuth, , Germany
Novartis Investigative Site, Berg, , Germany
Novartis Investigative Site, Berlin, , Germany
Novartis Investigative Site, Berlin, , Germany
Novartis Investigative Site, Bielefeld, , Germany
Novartis Investigative Site, Boblingen, , Germany
Novartis Investigative Site, Bochum, , Germany
Novartis Investigative Site, Bonn, , Germany
Novartis Investigative Site, Dresden, , Germany
Novartis Investigative Site, Erbach, , Germany
Novartis Investigative Site, Erlangen, , Germany
Novartis Investigative Site, Frankfurt, , Germany
Novartis Investigative Site, Freiburg, , Germany
Novartis Investigative Site, Hamburg, , Germany
Novartis Investigative Site, Hamburg, , Germany
Novartis Investigative Site, Hannover, , Germany
Novartis Investigative Site, Hannover, , Germany
Novartis Investigative Site, Heidelberg, , Germany
Novartis Investigative Site, Homburg, , Germany
Novartis Investigative Site, Itzehoe, , Germany
Novartis Investigative Site, Jena, , Germany
Novartis Investigative Site, Kassel, , Germany
Novartis Investigative Site, Leipzig, , Germany
Novartis Investigative Site, Leipzig, , Germany
Novartis Investigative Site, Muenchen, , Germany
Novartis Investigative Site, Muenster, , Germany
Novartis Investigative Site, Neuburg an der Donau, , Germany
Novartis Investigative Site, Oldenburg, , Germany
Novartis Investigative Site, Potsdam, , Germany
Novartis Investigative Site, Prien, , Germany
Novartis Investigative Site, Rostock, , Germany
Novartis Investigative Site, Schwendi, , Germany
Novartis Investigative Site, Siegen, , Germany
Novartis Investigative Site, Stade, , Germany
Novartis Investigative Site, Stadtroda, , Germany
Novartis Investigative Site, Teupitz, , Germany
Novartis Investigative Site, Ulm, , Germany
Novartis Investigative Site, Ulm, , Germany
Novartis Investigative Site, Unterhaching, , Germany
Novartis Investigative Site, Wiesbaden, , Germany
Novartis Investigative Site, Athens, , Greece
Novartis Investigative Site, Heraklion Crete, , Greece
Novartis Investigative Site, Thessaloniki, , Greece
Novartis Investigative Site, Budapest, HUN, Hungary
Novartis Investigative Site, Budapest, HUN, Hungary
Novartis Investigative Site, Budapest, HUN, Hungary
Novartis Investigative Site, Esztergom, HUN, Hungary
Novartis Investigative Site, Balassagyarmat, , Hungary
Novartis Investigative Site, Budapest, , Hungary
Novartis Investigative Site, Budapest, , Hungary
Novartis Investigative Site, Eger, , Hungary
Novartis Investigative Site, Miskolc, , Hungary
Novartis Investigative Site, Nyiregyhaza, , Hungary
Novartis Investigative Site, Veszprem, , Hungary
Novartis Investigative Site, Dublin 9, D9, Ireland
Novartis Investigative Site, Dublin 4, , Ireland
Novartis Investigative Site, Jerusalem, , Israel
Novartis Investigative Site, Ramat Gan, , Israel
Novartis Investigative Site, Genova, GE, Italy
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Cefalu, PA, Italy
Novartis Investigative Site, Roma, RM, Italy
Novartis Investigative Site, Roma, RM, Italy
Novartis Investigative Site, Roma, RM, Italy
Novartis Investigative Site, Roma, RM, Italy
Novartis Investigative Site, Roma, RM, Italy
Novartis Investigative Site, Napoli, , Italy
Novartis Investigative Site, Toon city, Ehime, Japan
Novartis Investigative Site, Asahikawa-city, Hokkaido, Japan
Novartis Investigative Site, Morioka, Iwate, Japan
Novartis Investigative Site, Kyoto-city, Kyoto, Japan
Novartis Investigative Site, Suita, Osaka, Japan
Novartis Investigative Site, Kawagoe, Saitama, Japan
Novartis Investigative Site, Tokorozawa city, Saitama, Japan
Novartis Investigative Site, Kodaira, Tokyo, Japan
Novartis Investigative Site, Ota-ku, Tokyo, Japan
Novartis Investigative Site, Shinjuku ku, Tokyo, Japan
Novartis Investigative Site, Shinjuku-ku, Tokyo, Japan
Novartis Investigative Site, Aomori, , Japan
Novartis Investigative Site, Chiba, , Japan
Novartis Investigative Site, Osaka, , Japan
Novartis Investigative Site, Riga, LV, Latvia
Novartis Investigative Site, Riga, , Latvia
Novartis Investigative Site, Riga, , Latvia
Novartis Investigative Site, Kaunas, LTU, Lithuania
Novartis Investigative Site, Klaipeda, , Lithuania
Novartis Investigative Site, Vilnius, , Lithuania
Novartis Investigative Site, Breda, CK, Netherlands
Novartis Investigative Site, Amsterdam, , Netherlands
Novartis Investigative Site, Eindhoven, , Netherlands
Novartis Investigative Site, Hoorn, , Netherlands
Novartis Investigative Site, Sittard-Geleen, , Netherlands
Novartis Investigative Site, Tilburg, , Netherlands
Novartis Investigative Site, Grudziadz, , Poland
Novartis Investigative Site, Katowice, , Poland
Novartis Investigative Site, Kielce, , Poland
Novartis Investigative Site, Konskie, , Poland
Novartis Investigative Site, Krakow, , Poland
Novartis Investigative Site, Lodz, , Poland
Novartis Investigative Site, Poznan, , Poland
Novartis Investigative Site, Warszawa, , Poland
Novartis Investigative Site, Amadora, , Portugal
Novartis Investigative Site, Braga, , Portugal
Novartis Investigative Site, Coimbra, , Portugal
Novartis Investigative Site, Lisboa, , Portugal
Novartis Investigative Site, Porto, , Portugal
Novartis Investigative Site, Constanta, Jud. Constanta, Romania
Novartis Investigative Site, Bucharest, , Romania
Novartis Investigative Site, Bucharest, , Romania
Novartis Investigative Site, Suceava, , Romania
Novartis Investigative Site, Targu Mures, , Romania
Novartis Investigative Site, Timisoara, , Romania
Novartis Investigative Site, Barnaul, , Russian Federation
Novartis Investigative Site, Kazan, , Russian Federation
Novartis Investigative Site, Moscow, , Russian Federation
Novartis Investigative Site, Moscow, , Russian Federation
Novartis Investigative Site, Novosibirsk, , Russian Federation
Novartis Investigative Site, Saint Petersburg, , Russian Federation
Novartis Investigative Site, St. Petersburg, , Russian Federation
Novartis Investigative Site, St. Petersburg, , Russian Federation
Novartis Investigative Site, Ufa, , Russian Federation
Novartis Investigative Site, Banska Bystrica, , Slovakia
Novartis Investigative Site, Bratislava, , Slovakia
Novartis Investigative Site, Bratislava, , Slovakia
Novartis Investigative Site, Martin, , Slovakia
Novartis Investigative Site, Nitra, , Slovakia
Novartis Investigative Site, Presov, , Slovakia
Novartis Investigative Site, Trencin, , Slovakia
Novartis Investigative Site, Trnava, , Slovakia
Novartis Investigative Site, Malaga, Andalucia, Spain
Novartis Investigative Site, Sevilla, Andalucia, Spain
Novartis Investigative Site, Hospitalet de Llobregat, Barcelona, Spain
Novartis Investigative Site, Barcelona, Cataluna, Spain
Novartis Investigative Site, Badalona, Catalunya, Spain
Novartis Investigative Site, Barcelona, Catalunya, Spain
Novartis Investigative Site, Barcelona, Catalunya, Spain
Novartis Investigative Site, Valencia, Comunidad Valenciana, Spain
Novartis Investigative Site, Valencia, Comunidad Valenciana, Spain
Novartis Investigative Site, El Palmar, Murcia, Spain
Novartis Investigative Site, Bilbao, Pais Vasco, Spain
Novartis Investigative Site, San Sebastian, Pais Vasco, Spain
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Goeteborg, , Sweden
Novartis Investigative Site, Stockholm, , Sweden
Novartis Investigative Site, Stockholm, , Sweden
Novartis Investigative Site, Aarau, CH, Switzerland
Novartis Investigative Site, Basel, , Switzerland
Novartis Investigative Site, Lausanne, , Switzerland
Novartis Investigative Site, Lugano, , Switzerland
Novartis Investigative Site, Luzern, , Switzerland
Novartis Investigative Site, St Gallen, , Switzerland
Novartis Investigative Site, Zuerich, , Switzerland
Novartis Investigative Site, Istanbul, TUR, Turkey
Novartis Investigative Site, Altunizade, , Turkey
Novartis Investigative Site, Haseki Istanbul, , Turkey
Novartis Investigative Site, Kocaeli, , Turkey
Novartis Investigative Site, Mecidiyekoy Istanbul, , Turkey
Novartis Investigative Site, Samsun, , Turkey
Novartis Investigative Site, Trabzon, , Turkey
Novartis Investigative Site, Salford, Manchester, United Kingdom
Novartis Investigative Site, Headington, Oxfordshire, United Kingdom
Novartis Investigative Site, Sheffield, South Yorkshire, United Kingdom
Novartis Investigative Site, Bristol, , United Kingdom
Novartis Investigative Site, Glasgow, , United Kingdom
Novartis Investigative Site, Leeds, , United Kingdom
Novartis Investigative Site, Leicester, , United Kingdom
Novartis Investigative Site, London, , United Kingdom
Novartis Investigative Site, London, , United Kingdom
Novartis Investigative Site, Newcastle Upon Tyne, , United Kingdom
Contact Details
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR
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