Spots Global Cancer Trial Database for Study of Gut Microbiome and Colorectal Tumors
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Trial Identification
Brief Title: Study of Gut Microbiome and Colorectal Tumors
Official Title: The Gut Microbiota in Conventional and Serrated Precursors of Colorectal Cancer
Study ID: NCT03297996
Interventions
Study Description
Brief Summary: Gut microbiota were assessed in 540 colonoscopy-screened adults by 16S rRNA gene sequencing of stool samples. Investigators compared gut microbiota diversity, overall composition, and normalized taxon abundance among these groups.
Detailed Description: Colorectal cancer is a heterogeneous disease arising from at least two precursors-the conventional adenoma (CA) and the serrated polyp. A relationship between the human gut microbiota and colorectal cancer has been shown; however, its relationship to the different early precursors of colorectal cancer is understudied. This study tested, for the first time, the relationship of the gut microbiota to specific colorectal polyp types.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
New York University School of Medicine, New York, New York, United States
Contact Details
Name: Jiyoung Ahn, MD
Affiliation: NYU Langone Health
Role: PRINCIPAL_INVESTIGATOR
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