Spots Global Cancer Trial Database for PRISM: Pre-Operative Radiotherapy and Immunotherapy for Sinonasal Melanoma

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Trial Identification

Brief Title: PRISM: Pre-Operative Radiotherapy and Immunotherapy for Sinonasal Melanoma

Official Title: PRISM: Pre-Operative Radiotherapy and Immunotherapy for Sinonasal Melanoma

Study ID: NCT05546827

Conditions

Sinonasal Melanoma

Interventions

Surgical resection

Study Description

Brief Summary: The goal of this clinical research study is to learn if pre-operative radiation therapy can help patients with sinonasal melanoma have better outcomes

Detailed Description: To determine the rate of pathologic response (\<50% viable tumor or \>50% fibrosis) for non-metastatic sinonasal melanoma patients having surgical resection after receiving neoadjuvant combination immunotherapy followed by radiation therapy.