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Brief Title: A Phase II Study of Sintilimab Combined With Anlotinib in Treatment of ED-SCLC
Official Title: Anti-PD-1 Antibody Sintilimab Combined With Anti-angeogensis Inhibitor Anlotinib in Treatment of Extensive-stage Disease Small Cell Lung Cancer After Failure of First Line Standard Therapy : a Single-arm Prospective Phase II Clinical Study
Study ID: NCT04967625
Brief Summary: This is a the researchers launched, single-center, prospective, open-label, single arm ,Phase II clinical study of Sintilimab combined with anlotinib in patients with extensive-stage disease small-cell lung cancer to evaluate the efficacy and safety. 23 patients are expected to be enrolled in this study.
Detailed Description: Subjects will receive sintilimab 200mg, IV, Q3W and anlotinib 12mg, PO, QD,d1-14, Q3W treatment until disease progression, unacceptable toxicity, or death.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Name: Guangyuan Lou
Affiliation: Zhejiang Cancer Hospital
Role: PRINCIPAL_INVESTIGATOR