Spots Global Cancer Trial Database for Panomic Approach to Immune-Connected Assays in Small Cell Lung Cancer
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Trial Identification
Brief Title: Panomic Approach to Immune-Connected Assays in Small Cell Lung Cancer
Official Title: Panomic Approach to Immune-Connected Assays in Small Cell Lung Cancer
Study ID: NCT05797493
Conditions
Interventions
Study Description
Brief Summary: The scope of the PICASSO project is to apply an innovative patient-based pan-omic approach to immune-assays, that will include multi-omics tumour characterization (genome, proteome, transcriptome), blood immune-cells and cytokine profiling, serological screening for paraneoplastic autoantibodies, clinical and metabolic measurements. The PICASSO project is aimed to validate in real world population the predictive role of SCLC transcriptomic classification (particularly, I-SCLC subtype) and to explore correlations with dynamic changes in peripheral blood immunity. Additionally, investigators expected to validate the predictive/prognostic role of emerging new variables, including metabolic-induced meta-inflammation alterations and subclinical auto-immunity.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Fondazione Policlinico Gemelli IRCCS, Rome, , Italy
Contact Details
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