Spots Global Cancer Trial Database for KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer
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Trial Identification
Brief Title: KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer
Official Title: An Open-Label, Multicenter, Phase 2 Study of the Safety and Efficacy of KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer (SCLC)
Study ID: NCT05027867
Interventions
Study Description
Brief Summary: This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with relapsed or refractory small cell lung cancer. This study will be conducted in 2 parts. Part 1 will evaluate two treatment arms, each with a different KRT-232 dose. Part 2 will continue the evaluation of the selected treatment arms from Part 1.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Florida Cancer Specialists - 3840 Broadway, Fort Myers, Florida, United States
Florida Cancer Specialists - 560 Jackson St, Suite 220, Saint Petersburg, Florida, United States
Florida Cancer Specialists, West Palm Beach, Florida, United States
Northwest Georgia Oncology Centers, Marietta, Georgia, United States
Hematology Oncology Clinic, Baton Rouge, Louisiana, United States
University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
Mark H Zangmeister Center - 3100 Plaza Properties Boulevard, Columbus, Ohio, United States
SCRI Tennessee Oncology Chattanooga, Chattanooga, Tennessee, United States
SCRI Tennessee Oncology Nashville, Nashville, Tennessee, United States
Flinders Medical Centre, Bedford Park, South Australia, Australia
Centre Hospitalier de Mulhouse - Hopital Emile Muller, Mulhouse, France/Haut-Rhin, France
Edog - Ico - Ppds, Angers, Maine-et-Loire, France
Hôpital Louis Pradel, Bron, Rhône, France
Hospices Civils de Lyon, Lyon, Rhône, France
Hôpital de La Croix Rousse, Pierre-Bénite, Rhône, France
EDOG - Institut Bergonie - PPDS, Bordeaux, , France
CHU de Grenoble, Grenoble, , France
Hopital Nord AP-HM, Marseille, , France
Klinik für Kardiologie, Angiologie und Pneumologie, Esslingen am Neckar, Baden-Württemberg, Germany
Lungenfachklinik Immenhausen, Immenhausen, Hessen, Germany
Evangelische Lungenklinik Berlin, Berlin, , Germany
Bacs Kiskun Megyei Korhaz, Kecskemét, Bács-Kiskun, Hungary
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do, Korea, Republic of
CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggido, Korea, Republic of
Clinica Universidad Navarra, Pamplona, Navarra, Spain
Hospital Universitario 12 de Octubre, Alicante, , Spain
Hospital General Universitario de Alicante, Alicante, , Spain
Hospital Universitario Vall d'Hebrón - PPDS, Barcelona, , Spain
Clinica Universidad Navarra - Madrid, Madrid, , Spain
Hospital Universitario La Paz, Madrid, , Spain
Hospital Regional Universitario de Malaga - Hospital Civil, Málaga, , Spain
Hospital Universitario Virgen Macarena, Sevilla, , Spain
Hospital Universitari i Politecnic La Fe de Valencia, Valencia, , Spain
Contact Details
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