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Brief Title: Study Comparing Amrubicin Versus Topotecan in Patients With Small Cell Lung Cancer Who Have Responded to Prior Therapy.
Official Title: A Randomized Phase 2 Trial Comparing Amrubicin Versus Topotecan as Second-Line Treatment in Patients With Extensive Small Cell Lung Cancer Sensitive to First-Line Chemotherapy
Study ID: NCT00319969
Brief Summary: The purpose of the study is to evaluate the objective tumor response rate of amrubicin or standard topotecan therapy when administered as second-line therapy to ED-SCLC patients who have chemotherapy sensitive recurrent or progressive.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Birmingham Hematology & Oncology, Birmingham, Alabama, United States
Hematology Oncology Associates, Phoenix, Arizona, United States
Alta Bates Medical Center - Comprehensive Cancer Center, Berkeley, California, United States
Moores UCSD Cancer Center, La Jolla, California, United States
Rocky Mountain Cancer Center - Denver, Denver, Colorado, United States
Rocky Mountain Cancer Center - Sky Ridge, Lone Tree, Colorado, United States
Ocala Oncology Center, Ocala, Florida, United States
Cancer Centers of Florida, PA, Ocoee, Florida, United States
John B. Amos Cancer Center, Columbus, Georgia, United States
Cancer Care & Hematology Specialists of Chicago, Niles, Illinois, United States
Oncology & Hematology of Central Illinois, Peoria, Illinois, United States
Blessing Cancer Center, Quincy, Illinois, United States
Central Indiana Cancer Centers, Indianapolis, Indiana, United States
Hope Center, Terre Haute, Indiana, United States
Norton Healthcare - Louisville Oncology, Louisville, Kentucky, United States
Sinai Hospital of Baltimore, Baltimore, Maryland, United States
Johns Hopkins Hospital - The Bunting Blaustein Cancer Research Building, Baltimore, Maryland, United States
Maryland Oncology Hematology, PA, Columbia, Maryland, United States
Alliance Hematology Oncology, PA - Carroll County Cancer Center, Westminster, Maryland, United States
Minnesota Oncology Hematology, PA, Minneapolis, Minnesota, United States
Missouri Cancer Associates, Columbia, Missouri, United States
Arch Medical Services - Center for Cancer Care & Research, St Louis, Missouri, United States
St. Joseph Oncology, Inc., St. Joseph, Missouri, United States
Hematology/Oncology Consultants, St. Louis, Missouri, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
New York Oncology Hematology, PC, Albany, New York, United States
SUNY Upstate Medical University - Regional Oncology Center, Syracuse, New York, United States
Northwestern Carolina Oncology & Hematology, Hickory, North Carolina, United States
Cancer Centers of North Carolina, Raleigh, North Carolina, United States
Willamette Valley Cancer Center, Eugene, Oregon, United States
Northwest Cancer Specialists, Portland, Oregon, United States
Medical Oncology Associates, Kingston, Pennsylvania, United States
Cancer Centers of the Carolinas, Greenville, South Carolina, United States
Texas Oncology Cancer Center, Austin, Texas, United States
Texas Cancer Center at Medical City, Dallas, Texas, United States
Texas Oncology, PA, Dallas, Texas, United States
Texas Oncology - Sammons Cancer Center, Dallas, Texas, United States
Texas Oncology, PA, Fort Worth, Texas, United States
Alison Cancer Center, Midland, Texas, United States
West Texas Cancer Center, Odessa, Texas, United States
Tyler Cancer Center, Tyler, Texas, United States
Texas Oncology Cancer Care & Research Center, Waco, Texas, United States
Texas Oncology, PA - Deke Slayton Cancer Center, Webster, Texas, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
Oncology & Hematology Associates of SW Virginia, Inc., Salem, Virginia, United States
Puget Sound Cancer Center, Seattle, Washington, United States
Northwest Cancer Specialists - Vancouver Cancer Center, Vancouver, Washington, United States
Name: Richard S Ungerleider, MD
Affiliation: Theradex
Role: STUDY_DIRECTOR