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Brief Title: Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancer
Official Title: Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancer (SCLC) Patients: a Phase I Trial.
Study ID: NCT01575782
Brief Summary: Chloroquine can make tumor cells less resistant to chemo/radiotherapy. In this trial chloroquine is given during radiotherapy. The dose is increased in cohorts of at least 3 patients.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
MAASTRO clinic, Maastricht, Limburg, Netherlands
Name: Philippe Lambin, MD, PhD
Affiliation: Maastro Clinic, The Netherlands
Role: PRINCIPAL_INVESTIGATOR