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Brief Title: Use of Elranatamab in Patients With High-risk Smoldering Multiple Myeloma
Official Title: A Multi-center, Open-label, Phase 2 Study of Elranatamab in Patients With High-risk Smoldering Multiple Myeloma
Study ID: NCT06183489
Brief Summary: This is a multicenter, single arm, open-label, Phase 2 study in high risk smoldering myeloma patients. The primary objective is to determine the efficacy of Elranatamab in patients with previously untreated high-risk SMM. The key-secondary objective is to determine the safety of Elranatamab in patients with previously untreated high-risk SMM.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Helsinki University Hospital, Helsinki, , Finland
CHD Vendée, La Roche-sur-Yon, , France
CHRU de Lille - Hopital Claude Huriez, Lille, , France
CHU Saint Eloi Département d'Hématologie Clinique, Montpellier, , France
CHU Hôtel-Dieu, 1, place Alexis Ricordeau, 44093 NANTES Cedex 1, FRANCE, Nantes, , France
CHU NICE - Hôpital Archet, Nice, , France
CHU Poitiers - Pôle régional de Cancérologie, Poitiers, , France
CHRU Hôpital Bretonneau, Tours, , France
Alexandra General Hospital -Department of Clinical Therapeutics N.K. Univ. of Athens, Athens, , Greece
AOU Consorziale Policlinico di Bari, Bari, , Italy
A.O. Papa Giovanni XXIII, Bergamo, , Italy
A.O.U. Careggi, Firenze, , Italy
A.O.U. Policlinico S. Martino - Ematologia, Genova, , Italy
Meldola-Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.), Meldola, , Italy
Ospedale Papardo, Messina, , Italy
A.O.U. Maggiore della Carità Novara, Novara, , Italy
A.O. di Padova, Padova, , Italy
A.O.U. di Parma - U.O Ematologia e CTMO, Parma, , Italy
Fondazione IRCCS Policlinico S. Matteo, Pavia, , Italy
Ospedale Santo Spirito, Roma, , Italy
Clinica Ematologica Azienda Sanitaria Universitaria Friuli Centrale, Udine, , Italy
Maastricht UMC, Maastricht, , Netherlands
St. Antonius Ziekenhuis, Nieuwegein, , Netherlands
Erasmus MC, Rotterdam, , Netherlands
Oslo Myeloma Center, Oslo, , Norway