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Brief Title: Evaluation of the Impact of the Update SMM Criteria on the Natural History of SMM to Establish New Recommendations.
Official Title: Evaluation of the Impact of the Update Multiple Myeloma Criteria on the Natural History of Smoldering Myeloma in Order to Establish New Recommendations About Follow-up and Prognostic Evaluation of Smoldering Myeloma (CARRISMM)
Study ID: NCT04144387
Brief Summary: This study is a prospective open label interventional multicenter study evaluating the impact of the update multiple myeloma criteria on the natural history of smoldering myeloma in order to establish new recommendations about follow up and prognostic evaluation of smoldering myeloma.
Detailed Description: In 2014, the International Myeloma Working Group (IMWG) proposed a revised classification of multiple myeloma (MM) and smoldering myeloma (SMM). Since the new definition of SMM proposed excludes "ultra-high risk SMM", the evolution profile of SMM will change. Therefore, investigators need to update their knowledge of SMM to optimize the management of patients. This project is expected to describe more precisely the new landscape of SMM. The results will help to establish new recommendations for the standard care of SMM and especially for defining accurate follow-up and risk stratifying.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Cliniques Universitaires Saint-Luc, Bruxelles, , Belgium
Institut Jules Bordet, Bruxelles, , Belgium
CHU UCL Namur ASBL Site Godinne, Yvoir, , Belgium
Centre Hospitalier, Abbeville, , France
CHU Amiens Sud, Amiens, , France
CHRU - Hôpital du Bocage, Angers, , France
Ch Annecy Genevois, Annecy, , France
Centre Hospitalier d'Argenteuil Victor Dupouy, Argenteuil, , France
CH d'Arras, Arras, , France
Centre Hospitalier de Auch, Auch, , France
Centre Hospitalier H. Duffaut, Avignon, , France
Centre hospitalier de la Côte Basque, Bayonne, , France
Hôpital Nord Franche Comté, Belfort, , France
Centre Hospitalier Simone Veil, Blois, , France
Hôpital Avicenne, Bobigny, , France
Institut Bergonié - Pavillon Saint Genès - 1er étage, Bordeaux, , France
Polyclinique Bordeaux Nord Aquitaine, Bordeaux, , France
Centre hospitalier Pierre Oudot, Bourgoin-Jallieu, , France
CHRU Brest - Hôpital A. Morvan, Brest, , France
CHU Caen - Côte de Nacre, Caen, , France
Centre Hospitalier, Cannes, , France
CH René Dubos, Cergy Pontoise, , France
Médipôle de Savoie, Challes-les-Eaux, , France
Centre Hospitalier William Morey, Chalon-sur-Saône, , France
CH Chambéry, Chambéry, , France
Hôpital d'Instruction des Armées Percy, Clamart, , France
Centre Hospitalier Sud Francilien, Corbeil-Essonnes, , France
CHU Henri Mondor, Créteil, , France
Centre Hospitalier, Dax, , France
CHU François Mitterand, Dijon, , France
Centre Hospitalier de Dunkerque, Dunkerque, , France
Hôpital de Fréjus, Fréjus, , France
CHU de Grenoble, Grenoble, , France
Institut Daniel Hollard, Grenoble, , France
CHD Vendée, La Roche-sur-Yon, , France
Groupe Hospitalier de La Rochelle, La Rochelle, , France
Hospital Jacques Monod, Le Havre, , France
Centre Hospitalier, Le Mans, , France
Centre Hospitalier, Lens, , France
Centre hospitalier Robert Boulin, Libourne, , France
CHRU Hôpital Claude Huriez, Lille, , France
Centre Hospitalier Universitaire (CHU) de Limoges, Limoges, , France
Hôpital du Scorff, Lorient, , France
Centre Hospitalier Lyon Sud, Lyon, , France
Centre Léon Bérard, Lyon, , France
CH Meaux, Meaux, , France
Hospital Sainte Blandine, Metz, , France
Hôpital de Mercy (CHR Metz-Thionville), Metz, , France
Centre de Recherche Clinique / GHT des Landes, Mont-de-Marsan, , France
Clinique du Parc, Montpellier, , France
Hopital Saint Eloi - CHU Montpellier, Montpellier, , France
Hôpital E. Muller, Mulhouse, , France
CHRU Hôpitaux de Brabois, Nancy, , France
Centre Catherine de Sienne, Nantes, , France
CHRU Hôtel Dieu, Nantes, , France
Hôpital Archet 1, Nice, , France
CHU Carémeau, Institut de Cancérologie du Guard, Nîmes, , France
CH La Source, Orléans, , France
CHU Hôpital Saint Antoine, Paris, , France
Hôpital Cochin, Paris, , France
Hôpital Necker, Paris, , France
Hôpital Saint Louis, Paris, , France
La Pitié, Paris, , France
CH Saint Jean, Perpignan, , France
CHRU - Hôpital du Haut Lévêque - Centre François Magendie, Pessac, , France
CHU Poitiers - Pôle régional de Cancérologie, Poitiers, , France
Centre Hospitalier de Perigueux, Périgueux, , France
Centre Hospitalier de Quimper Cornouaille, Quimper, , France
Hôpital Robert Debré, Reims, , France
CHRU Hôpital de Pontchaillou, Rennes, , France
Hôpital Privé Sévigné, Rennes, , France
Centre Hospitalier Jacques Puel, Rodez, , France
CH Roubaix, Roubaix, , France
Centre Henri Becquerel, Rouen, , France
Centre Hospitalier Yves Le Foll, Saint-Brieuc, , France
CH Saint Malo, Saint-Malo, , France
Institut de Cancérologie Lucien Neuwirth, Saint-Priest, , France
Centre Hospitalier, Saint-Quentin, , France
CHU Strasbourg - Hôpital de Hautepierre, Strasbourg, , France
Strasbourg Oncologie Libérale, Strasbourg, , France
Centre hospitalier de Tarbes, Tarbes, , France
Hôpital Inter-Armées Ste Anne, Toulon, , France
Pôle IUCT Oncopole CHU, Toulouse, , France
CHRU Hôpital Bretonneau - Centre Henry Kaplan, Tours, , France
Centre Hospitalier de Troyes, Troyes, , France
Centre Hospitalier de Valence, Valence, , France
Centre Hospitalier, Valenciennes, , France
CH Bretagne Atlantique Vannes et Auray - P. Chubert, Vannes, , France
CHV André Mignot - Université de Versailles, Versailles, , France
Centre Hospitalier Princesse Grace, Monaco, , Monaco
Name: Pr. Olivier Decaux
Affiliation: Rennes University Hospital
Role: PRINCIPAL_INVESTIGATOR