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Spots Global Cancer Trial Database for A Study of Palifosfamide Tris Plus Doxorubicin Versus Doxorubicin in Unresectable or Metastatic Soft-tissue Sarcoma

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Trial Identification

Brief Title: A Study of Palifosfamide Tris Plus Doxorubicin Versus Doxorubicin in Unresectable or Metastatic Soft-tissue Sarcoma

Official Title: A Phase II Multicenter, Parallel Group, Randomized Study of Palifosfamide Tris Plus Doxorubicin Versus Doxorubicin in Subjects With Unresectable or Metastatic Soft-tissue Sarcoma

Study ID: NCT00718484

Study Description

Brief Summary: This is a randomized, controlled trial to evaluate the clinical benefit of palifosfamide tris administered with doxorubicin in combination, compared with single-agent doxorubicin administered in subjects diagnosed with unresectable or metastatic soft-tissue sarcoma (STS). Subjects who meet the entry criteria will be randomized into 1 of 2 arms: either to receive palifosfamide tris plus doxorubicin or treatment with single-agent doxorubicin. Subjects will be anthracyclin naïve.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

, Santa Monica, California, United States

, Washington, District of Columbia, United States

, Tampa, Florida, United States

, Coeur d'Alene, Idaho, United States

, Chicago, Illinois, United States

, Park Ridge, Illinois, United States

, Iowa city, Iowa, United States

, Lenaxa, Kansas, United States

, Albuquerque, New Mexico, United States

, New York, New York, United States

, Durham, North Carolina, United States

, Portland, Oregon, United States

, Philadelphia, Pennsylvania, United States

, Memphis, Tennessee, United States

, Nashville, Tennessee, United States

, San Antonio, Texas, United States

, Salt Lake City, Utah, United States

, Seattle, Washington, United States

, Milan, , Italy

, Padova, , Italy

, Torino, , Italy

, Cluj-Napoca, , Romania

, Lasi, , Romania

Contact Details

Name: Jonathan J Lewis, MD, PhD

Affiliation: ZIOPHARM Oncology, Inc

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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