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Spots Global Cancer Trial Database for Hypofractionated Radiotherapy for Soft Tissue Sarcomas

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Trial Identification

Brief Title: Hypofractionated Radiotherapy for Soft Tissue Sarcomas

Official Title: Phase 2 Trial of Hypofractionated Radiotherapy for Soft Tissue Sarcomas

Study ID: NCT03972930

Study Description

Brief Summary: One of the main challenges in treating sarcomas with radiation is the toxicity to normal structures around the sarcoma. Early reports suggest Hypofractionated Radiotherapy will be safe and effective for treatment of soft tissue sarcomas. However, given the rarity of this disease, the diversity of histological sub-types, and the variety of locations where these can occur (anywhere in the body), more data is needed to provide understanding of the safety and efficacy of hypofractionated radiotherapy for treatment of this disease. The hypothesis is that by using hypofractionated radiotherapy, highly conformal high dose radiation can be delivered to soft tissue sarcomas, while respecting established normal tissue constraints and that local control rates will be greater than historical rates reported with conventional fractionation. Eligible participants with biopsy proven soft tissue sarcoma will be on study for up to 60 months.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Wisconsin, Madison, Wisconsin, United States

Contact Details

Name: Zachary Morris, MD, PhD

Affiliation: University of Wisconsin, Madison

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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