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Brief Title: Study to Assess Safety, Tolerability and PK of AZD1480 in Patients With Solid Tumours
Official Title: A Phase I, Open-Label, Multi-Center, Dose-Escalation Study to Assess the Safety and Tolerability, and Pharmacokinetics of AZD1480 Administered as Daily Oral Monotherapy in Patients With Advanced Solid Malignancies in the Escalation Phase and EGFR or ROS Mutant NSCLC or Non-Smokers With Lung Metastasis in the Expansion Phase.
Study ID: NCT01112397
Brief Summary: This study is being conducted to assess the safety, tolerability and PK of AZD1480 in patients with advanced solid malignancies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Aurora, Colorado, United States
Research Site, Detroit, Michigan, United States
Research Site, Philadelphia, Pennsylvania, United States
Name: Gregory Curt, MD
Affiliation: AstraZeneca
Role: STUDY_CHAIR