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Brief Title: GT201 Injection For The Treatment Of Advanced Solid Tumors
Official Title: A Single-Arm Phase I/II Clinical Study of Autologous Tumor-Infiltrating Lymphocyte Injection (GT201) for The Treatment Of Advanced Solid Tumors
Study ID: NCT06144671
Brief Summary: Expected to complete 7 to 18 evaluable subjects (patients with advanced solid tumors),3 dose groups.A modified "3+3" dose-escalation design is utilized,This includes both accelerated dose escalation and traditional "3+3" dose escalation.The first dose group is accelerated titration,The first dose group is an accelerated titration of 1 to 6 evaluable subjects;The second and third dose groups are based on the traditional "3+3" dose-escalation principle,The second and third dose groups are based on the traditional "3+3" dose-escalation principle, with 3 to 6 evaluable subjects enrolled respectively.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The fifth medical center of the General Hospital of the Chinese people's Liberation Army, Beijing, Beijing, China
Union Hospital Tongji Medical College Huazhong University Of Science And Technology, Wuhan, Hubei, China
Shandong Cancer Hospital, Jinan, Shandong, China
West China Hospital Sichuan University, Chengdu, Sichuan, China