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Spots Global Cancer Trial Database for PD-1 Antibody Expressing CAR T Cells for Mesothelin Positive Advanced Malignancies

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: PD-1 Antibody Expressing CAR T Cells for Mesothelin Positive Advanced Malignancies

Official Title: PD-1 Antibody Expressing Chimeric Antigen Receptor T Cells for Mesothelin Positive Advanced Malignancies

Study ID: NCT03030001

Study Description

Brief Summary: This is a single-arm, open-label, one center, dose escalation clinical study, to determine the safety and efficacy of infusion of autologous T cells engineered to express immune checkpoint antibody and chimeric antigen receptor targeting mesothelin in adult patients with mesothelin positive, recurrent or refractory malignant tumors.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Ningbo No.5 Hospital (Ningbo Cancer Hospital), Ningbo, Zhejiang, China

Contact Details

Name: Qijun Qian, PhD

Affiliation: Shanghai Cell Therapy Engineering Research Institute

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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