Spots Global Cancer Trial Database for Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)
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Trial Identification
Brief Title: Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)
Official Title: A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)
Study ID: NCT03822117
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Cancer Treatment Centers of America, Goodyear, Arizona, United States
Mayo Clinic Hospital, Phoenix, Arizona, United States
The University of Arizona Cancer Center, Tucson, Arizona, United States
Chao Family Comprehensive Cancer Center University of California, Irvine, Orange, California, United States
Stanford Cancer Center, Palo Alto, California, United States
John Wayne Cancer Institute, Santa Monica, California, United States
St. Joseph Heritage Healthcare, Santa Rosa, California, United States
Florida Cancer Specialists & Research Institute, Fort Myers, Florida, United States
Mayo Clinic Jacksonville, Jacksonville, Florida, United States
Florida Cancer Specialists, Saint Petersburg, Florida, United States
Florida Cancer Specialists, Tallahassee, Florida, United States
Florida Cancer Specialists, West Palm Beach, Florida, United States
Illinois Cancer Specialists, Arlington Heights, Illinois, United States
Edward H Kaplan & Associates, Skokie, Illinois, United States
Carle Cancer Center, Urbana, Illinois, United States
Cancer Treatment Centers of America, Zion, Illinois, United States
Indiana University Health - Arnett Cancer Care, Lafayette, Indiana, United States
University of Iowa, Iowa City, Iowa, United States
University of Kansas Cancer Center, Westwood, Kansas, United States
Ochsner Clinic, New Orleans, Louisiana, United States
Central Maine Medical Center, Lewiston, Maine, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Umass Memorial Medical Center, Inc., Worcester, Massachusetts, United States
Mayo Clinic Rochester, Rochester, Minnesota, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States
Summit Medical Group, Florham Park, New Jersey, United States
Winthrop University Hospital, Mineola, New York, United States
Oncology Specialists of Charlotte, Charlotte, North Carolina, United States
Duke Cancer Center, Durham, North Carolina, United States
Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, United States
Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
Southwestern Regional Medical Center, Tulsa, Oklahoma, United States
Cancer Institute of Greenville Health System, Greenville, South Carolina, United States
The West Clinic Pc, Germantown, Tennessee, United States
University of Texas Southwestern Medical Center, Dallas, Texas, United States
Houston Methodist Hospital, Houston, Texas, United States
Joe Arrington Cancer Center, Lubbock, Texas, United States
Virginia Cancer Specialists, Pc, Fairfax, Virginia, United States
Virginia Oncology Associates-Lake Wright, Norfolk, Virginia, United States
Seattle Cancer Care Alliance, Seattle, Washington, United States
Multicare Institute For Research & Innovation, Tacoma, Washington, United States
West Virginia University Hospitals Inc, Morgantown, West Virginia, United States
University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, United States
The Finsen Centre National Hospital, Copenhagen, , Denmark
Institut Bergonie, Bordeaux, , France
CENTRE GEORGES FRAN�OIS LECLERC, Dijon Cedex, , France
Centre Antoine Lacassagne, Nice, , France
Hospital Saint Louis, Paris, , France
A.P.H. Paris Hopital Cochin, Paris, , France
Institut Universitaire Du Cancer de Toulouse Oncopole, Toulouse, , France
University Medical Center Freiburg, Freiburg, , Germany
University Medical Centre Hamburg-Eppendorf, Centre of Oncology, Hamburg, , Germany
Universitatsklinikum Koln, Koln, , Germany
University Hospital Grosshadern Munich, Munich, , Germany
Universitaetsklinikum in Tubingen, Tubingen, , Germany
Ha Emek Medical Center, Afula, , Israel
Rambam Health Care Campus, Haifa, , Israel
Hadassah Hebrew University Medical Center Ein Karem Hadassah, Jerusalem, , Israel
Rabin Medical Center - Beilinson Hospital, Petach Tikva, , Israel
Assaf Harofeh Medical Center, Zerifin, , Israel
L AZIENDA OSPEDALIERO-UNIVERSITARIA DI BOLOGNA POLICLINICO S. ORSOLA � MALPIGHI, Bologna, , Italy
Fondazione Del Piemonte Per L Oncologia Ircc Candiolo, Candiolo, , Italy
Fondazione Irccs Istituto Nazionale Dei Tumori, Milan, , Italy
Istituto Nazionale Tumori Irccs Fondazione Pascale, Napoli, , Italy
Istituto Nazionale Tumori Regina Elena Irccs, Roma, , Italy
Centro Ricerche Cliniche Di Verona (Crc), Verona, , Italy
National Hospital Organization Kyushu Cancer Center, Fukuoka, , Japan
Kanazawa University Hospital, Ishikawa, , Japan
Kobe University Hospital, Kobe, , Japan
Tohoku University Hospital, Sendai-shi, , Japan
Keio University Hospital, Shinjuku-ku, , Japan
Shizuoka Cancer Center, Shizuoka, , Japan
Kanagawa Cancer Center, Yokohama-shi, , Japan
National Cancer Center, Goyang-si, , Korea, Republic of
Seoul National University Bundang Hospital, Seongnam-si, , Korea, Republic of
Severance Hospital Yonsei University Health System, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Hospital General Universitario Vall D Hebron, Barcelona, , Spain
Hospital Clinic I Provincial, Barcelona, , Spain
Centro Integral Oncologico Clara Campal (Ciocc), Madrid, , Spain
Hospital Regional Universitario de Malaga, Malaga, , Spain
Clinica Universidad de Navarra (Cun), Pamplona, , Spain
Hospital Universitario Marques de Valdecilla, Santander, , Spain
Hospital Universitario Y Politcnico de La Fe, Valencia, , Spain
Inselspital - Universitaetsspital Bern, Bern, , Switzerland
Universitatsspital Zurich, Zuerich, , Switzerland
University College London Hospitals (Uclh), London, , United Kingdom
Imperial College Healthcare Nhs Trust - Hammersmith Hospital, London, , United Kingdom
Sarah Cannon Research Institute, London, , United Kingdom
Contact Details
Name: Peter Langmuir, MD
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR
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