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Brief Title: Combination Chemotherapy in Treating Older Patients With Solid Tumour,
Official Title: Study of a Scale Predicting the Feasibility of Chemotherapy in Patients Aged 75 Years or Older With Solid Tumour
Study ID: NCT00664911
Brief Summary: RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This clinical trial is studying how well combination chemotherapy works in treating older patients with solid tumour.
Detailed Description: OBJECTIVES: Primary * To determine a prognostic scale of the feasibility of chemotherapy (at least two-thirds of the dose intensity usually administered) in patients aged 75 years or older with solid tumour. Secondary * To evaluate the efficacy, in terms of clinical and/or biological response, of treatments administered. * To evaluate the incidence of severe (grade 3-4) toxicity. OUTLINE: This is a multicenter study. Patients receive one of the following regimens according to cancer diagnosis and principal investigator preference. All regimens last 3 months.
Minimum Age: 75 Years
Eligible Ages: OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Centre Radiotherapie Oncologie Moyenne Garonne, Agen, , France
Centre Hospitalier de Castelluccio, Ajaccio, , France
Centre Hospitalier d'Ardeche Meridionale, Aubenas, , France
Centre Hospitalier d'Auxerre, Auxerre, , France
Institut Sainte Catherine, Avignon, , France
Hopital Duffaut, Avignon, , France
Centre Hospitalier de Beauvais, Beauvais, , France
Clinique des Cedres, Cornebarrieu, , France
Centre Medico-Chirurgical et Obstetrique d'Evry, Evry, , France
Hopital Clarac, Fort de France Cedex, , France
Centre Hospitalier Intercommunal des Alpes du Sud, Gap, , France
Centre Hospitalier de Lagny, Lagny Sur Marne, , France
Centre Hospitalier St. Joseph St. Luc, Lyon, , France
Hopital Prive Jean Mermoz, Lyon, , France
Centre Hospitalier Chanaux, Macon, , France
Centre Hospitalier de Montelimar, Montelimar, , France
Hopital Bichat - Claude Bernard, Paris, , France
Hopital de la Croix St. Simon, Paris, , France
Hopital Saint Antoine, Paris, , France
Hopital Tenon, Paris, , France
Hopital Rene Dubos, Pontoise, , France
Institut Jean Godinot, Reims, , France
Centre Hospitalier Prive Saint-Gregoire, Saint-Gregoire, , France
Centre Hospitalier de Saint-Quentin, Saint-Quentin, , France
Centre Hospitalier de Semur en Auxois, Semur en Auxois, , France
C.H. Senlis, Senlis, , France
Hopital Foch, Suresnes, , France
Centre hospitalier de Tonnerre, Tonnerre, , France
Centre Hospitalier Villeneuve Saint Georges, Villeneuve Saint Georges, , France
Name: Elisabeth Carola, MD
Affiliation: C.H. Senlis
Role: STUDY_CHAIR