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Brief Title: Study of AK119 in Subjects With Advanced Solid Tumors
Official Title: A Phase I, Multicenter, Open-Label, Dose-escalation and Dose-exploration Study to Evaluate the Safety, Pharmacokinetics, and Anti-tumor Activity of of AK119 (CD73) in Subjects With Advanced Solid Tumors
Study ID: NCT05173792
Brief Summary: This is Phase 1, Multicenter, Open-Label, Dose-Escalation and Dose-Exploration Study to Evaluate the Safety, Pharmacokinetics, and Anti-tumor Activity of AK119 (Anti-CD73) in Subjects with Advanced or Metastatic Solid Tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Fudan University Zhongshan Hospital, Shanghai, , China
Tianjin Medical University Cancer Institute & Hospital, Tianjin, , China
Name: Jihui Hao, PhD
Affiliation: Tianjin Medical University Cancer Insitute & Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Tianshu Liu
Affiliation: Shanghai Zhongshan Hospital
Role: PRINCIPAL_INVESTIGATOR