Spots Global Cancer Trial Database for Study of Magrolimab in Patients With Solid Tumors
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Trial Identification
Brief Title: Study of Magrolimab in Patients With Solid Tumors
Official Title: A Phase 2, Multi-Arm Study of Magrolimab in Patients With Solid Tumors
Study ID: NCT04827576
Conditions
Study Description
Brief Summary: The goals of this clinical study are to learn about the safety, tolerability, dosing and effectiveness of magrolimab in combination with docetaxel in patients with solid tumors.
Detailed Description: This study will consist of a Safety Run-in Cohort 1 (magrolimab + docetaxel combination). After completion of the Safety Run-in Cohort 1, Phase 2 Cohort 1 will occur as follows: * Phase 2 Cohort 1: a cohort of participants with solid tumors (metastatic non-small cell lung cancer (mNSCLC) (Phase 2 Cohort 1a), metastatic urothelial cancer (mUC) (Phase 2 Cohort 1b), and metastatic small cell lung cancer (mSCLC) (Phase 2 Cohort 1c).
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Cancer Treatment Centers of America, Goodyear, Arizona, United States
UC San Diego Moores Cancer Center, La Jolla, California, United States
Providence Saint John's Health Center, Santa Monica, California, United States
St. Jude Hospital Yorba dba St. Joseph Heritage Healthcare, Santa Rosa, California, United States
University of Miami, Deerfield Beach, Florida, United States
Tallahassee Memorial Healthcare Cancer Center, Tallahassee, Florida, United States
University Center and Blood Center,LLC., Athens, Georgia, United States
Southeastern regional Medical Center, Newnan, Georgia, United States
Saint Alphonsus Cancer Institute Caldwell, Caldwell, Idaho, United States
Orchard Healthcare Research Inc, Skokie, Illinois, United States
University of Iowa Hospitals & Clinics, Iowa City, Iowa, United States
University of Michigan, Ann Arbor, Michigan, United States
Virginia Piper Cancer Center (Alliant Health), Saint Paul, Minnesota, United States
Comprehensive Cancer Centers of Nevada- Twain Office, Las Vegas, Nevada, United States
Astera Cancer Care, East Brunswick, New Jersey, United States
Oregon Health & Science University, Portland, Oregon, United States
Charleston Oncology, Charleston, South Carolina, United States
Mary Crowley Cancer Research, Dallas, Texas, United States
MD Anderson Cancer Center, Dallas, Texas, United States
Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States
Medical Oncology Associates,PS (dba Summit Cancer Center) (includes IP Shipment), Spokane, Washington, United States
Institut Bergonie, Bordeaux, , France
Centre Georges François Leclerc, Dijon, , France
Centre Hospitalier Regional Universitaire de Lille, Lille, , France
Centre LÃon BÃrard Centre RÃgional de Lutte Contre Le Cancer, Lyon, , France
Hopital Nord AP-HM, Marseille, , France
Centre de Lutte Contre le Cancer (CLCC) - Centre Antoine Lacassagne (CAL) - Site Est, Nice, , France
Hôpital de la Pitié Salpétrière, Paris, , France
Centre Hospitalier Lyon-Sud, Pierre-benite, , France
Institut de Cancérologie de l'Ouest (ICO) - Saint-Herblain, Saint Herblain, , France
Centrum Onkologii im. Prof. Franciszka Lukaszczyka w Bydgoszczy, Bydgoszcz, , Poland
Instytut Centrum Zdrowia Matki Polki, Lodz, , Poland
Wojewodzki Szpital Specjalistyczny w Siedlcach, Siedlce, , Poland
Instituto de Investigacion Oncologica Vall de Hebron, Barcelona, , Spain
Hospital del Mar, Barcelona, , Spain
Hospital Quironsalud Barcelona, Barcelona, , Spain
Hospital De La Santa Creu I Sant Pau, Barcelona, , Spain
Hospital Universitario de Jaen, Jaen, , Spain
Hospital General Universitario Gregorio Maranon, Madrid, , Spain
MD Anderson Cancer Center, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Hospital HM Sanchinarro, Madrid, , Spain
Hospital Regional Universitario de Malaga, Malaga, , Spain
Clinica Universidad de Navarra, Pamplona, , Spain
Hospital Universitario Virgen Macarena, Sevilla, , Spain
Hospital Universitario Virgen del Rocio, Sevilla, , Spain
Hospital Universitari i Politecnic La Fe, Valencia, , Spain
Barts Health NHS Trust, London, , United Kingdom
Guy's and St Thomas' NHS Foundation Trust, London, , United Kingdom
Contact Details
Name: Gilead Study Director
Affiliation: Gilead Sciences
Role: STUDY_DIRECTOR
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