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Spots Global Cancer Trial Database for A PhaseI Study of HL-085 Plus Vemurafenib in Solid Tumor With BRAF V600 Mutation

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Trial Identification

Brief Title: A PhaseI Study of HL-085 Plus Vemurafenib in Solid Tumor With BRAF V600 Mutation

Official Title: A Phase I, Single Arm, Dose Escalation Study to Evaluate Safety, Pharmacokinetics and Preliminary Efficacy of HL-085 Plus Vemurafenib in Patients With BRAF V600 Mutant Advanced Solid Tumor

Study ID: NCT03781219

Conditions

Solid Tumor

Interventions

HL-085
Vemurafenib

Study Description

Brief Summary: This is a phase I, open-label, dose escalation study to evaluate tolerability, safety, pharmacokinetics and efficacy in patients with BRAF V600 mutant advanced solid tumor by HL-085 plus Vemurafenib treatment.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Cancer Hospital Chinese Academy of Medical Science, Beijing, Beijing, China

Beijing Oncology Hospital, Beijing, Beijing, China

Henan Province Oncology Hospital, Zhengzhou, Henan, China

First Affiliated Hospital, Medicine School of Zhejiang University, Hangzhou, Zhejiang, China

Contact Details

Name: Hongqi Tian, Ph.D

Affiliation: Shanghai Kechow Pharma, Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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