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Spots Global Cancer Trial Database for Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)

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Trial Identification

Brief Title: Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)

Official Title: A Phase II Basket Study of the Oral Selective Pan-FGFR Inhibitor Debio 1347 in Subjects With Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3

Study ID: NCT03834220

Conditions

Solid Tumor

Interventions

Debio 1347

Study Description

Brief Summary: The primary objective of this study is to assess the efficacy of Debio 1347 in terms of objective response rate (ORR) in participants with solid tumors harboring fibroblast growth factor receptor (FGFR)1-3 gene fusion/rearrangement.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Ironwood Cancer & Research Centers - Scottsdale, Scottsdale, Arizona, United States

University of Arizona Cancer Center, Tucson, Arizona, United States

Moores UCSD Cancer Center, La Jolla, California, United States

University of California San Francisco, San Francisco, California, United States

Sarcoma Oncology Center, Santa Monica, California, United States

H. Lee Moffitt Cancer Center and Research Institute, Inc, Tampa, Florida, United States

James Graham Brown Cancer Center, Louisville, Kentucky, United States

Tulane University Cancer Center, New Orleans, Louisiana, United States

The John Hopkins Hospital, Baltimore, Maryland, United States

Massachusetts General Hospital, Boston, Massachusetts, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

University of Michigan, Ann Arbor, Michigan, United States

Memorial Sloan Kettering Cancer Center, Middletown, New Jersey, United States

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

Memorial Sloan Kettering Cancer Center, Harrison, New York, United States

Memorial Sloan-Kettering Hospital, New York, New York, United States

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

UC Health, LLC., Cincinnati, Ohio, United States

The Ohio State University Wexner Medical Center - James Cancer Hospital, Columbus, Ohio, United States

CTCA Cancer Treatment Centers, Tulsa, Oklahoma, United States

West Penn - Allegheny Oncology Network, Pittsburgh, Pennsylvania, United States

MD Anderson Cancer Center, Houston, Texas, United States

University of Utah Hospitals & Clinics, Salt Lake City, Utah, United States

Fred Hutchinson/Seattle Care Alliance, Seattle, Washington, United States

University of Wisconsin, Madison, Wisconsin, United States

Southern Highlands Private Hospital, Bowral, , Australia

Peninsula and Southeast Oncology (PASO), Frankston, , Australia

Linear Clinical Research, B Block Sir Charles Gairdner Hospital, Nedlands, , Australia

John Flynn Private Hospital, Tugun, , Australia

LKH - Universitätsklinikum der PMU Salzburg, Salzburg, , Austria

Landesklinikum Wiener Neustadt, Wiener Neustadt, , Austria

Hospital de Caridade de Ijuí, Avenida David J Martins, Ijuí, , Brazil

Hospital de Clínicas de Porto Alegre, Rio Grande, , Brazil

CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia, Santo André, , Brazil

ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, Avenida Doutor Arnaldo, São Paulo, , Brazil

MHAT - Dobrich, Dobrich, , Bulgaria

Complex Oncological Center - Plovdiv, EOOD, Plovdiv, , Bulgaria

MHAT "Serdika", EOOD, Sofia, , Bulgaria

General Hospital Varazdin, Varaždin, , Croatia

University Hospital Centre, Sestre Milosrdnice, Zagreb, , Croatia

Fakultni nemocnice u sv. Anny v Brne, Brno, , Czechia

Fakultni nemocnice Hradec Kralove, Hradec Králové, , Czechia

Fakultni nemocnice Olomouc, Olomouc, , Czechia

Thomayerova nemocnice, Prague, , Czechia

Fakultni nemocnice Kralovske Vinohrady, Praha, , Czechia

Ålborg Universitets Hospital, Aalborg, , Denmark

Herlev Hospital, Herlev, , Denmark

Odense Universitetshospital, Odense, , Denmark

Docrates Syöpäsairaala, Helsinki, , Finland

Helsinki University Hospital, Helsinki, , Finland

ICO - Site Paul Papin, Angers, , France

CHU Bordeaux - Hôpital Saint André, Groupe Hospitalier Sud - Hôpital Haut-Lévêque, Bordeaux, , France

Centre Oscar Lambret, Lille, , France

Groupe Hospitalier Sud - Hôpital Haut Lévêque, Pessac, , France

ICO - Site René Gauducheau, Saint-Herblain, , France

Institut Gustave Roussy, Villejuif, , France

General Hospital of Athens Laiko, Athens, , Greece

General Hospital of Athens of Chest Diseases "SOTIRIA", Athens, , Greece

General Hospital of Athens "Alexandra", Athens, , Greece

University General Hospital of Ioannina, Ioánnina, , Greece

Seoul National University Bundang Hospital, Department of Oncology Medical office, Gyeonggi-do, , Korea, Republic of

The Catholic University of Korea, St. Vincent's Hospital, CRC Room, 3F, Gyeonggi-do, , Korea, Republic of

Gachon University Gil Medical Center, CRC Room, 18F, Artificial intelligence hospital, Incheon, , Korea, Republic of

Korea University Anam Hospital, Seoul, , Korea, Republic of

Seoul National University Hospital (SNUH), Seoul, , Korea, Republic of

Ajou University Hospital, CRC room, Clinical Trial Center, Suwon, , Korea, Republic of

VU Medisch Centrum, Amsterdam, , Netherlands

Haga Ziekenhuis, Den Haag, , Netherlands

Akershus University Hospital, Lørenskog, , Norway

Radiumhospitalet, Montebello, Oslo, , Norway

Cebu Doctors' University Hospital (CDUH), Research Office, Cebu City, , Philippines

Philippine General Hospital, Clinical Trial Unit Room 5, Medical Research Laboratory, Ermita, , Philippines

St. Luke's Medical Center, Human Cancer Biobank Research Center, Quezon City, , Philippines

Szpital Kliniczny im.Heliodora Swiecickiego Uniwersytetu Medycznego im.K. Marcinkowskiego w Poznaniu, Poznań, , Poland

MTZ Clinical Research, Warszawa, , Poland

Centrum Onkologii-Instytut im.M.Sklodowskiej Curie, Warszawa, , Poland

S.C Delta Health Care S.R.L, Bucuresti, , Romania

S.C Medisprof S.R.L., Cluj-Napoca, , Romania

S.C Centrul de Oncologie Sf. Nectarie S.R.L., Craiova, , Romania

S.C Oncocenter Oncologie Clinica S.R.L., Timişoara, , Romania

SBIH of Arkhangelsk region "Arkhangelsk Clinical Oncological Dispensary", Arkhangel'sk, , Russian Federation

TSBHI "Altai Territorial oncological dispensary", Barnaul, , Russian Federation

LLC Evimed, Chelyabinsk, , Russian Federation

FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin", Moscow, , Russian Federation

BHI of Omsk region "Clinical Oncology Dispensary", Omsk, , Russian Federation

Tomsk Research Instutite of Oncology, Tomsk, , Russian Federation

Singapore National Cancer Center (SNCC), Singapore, , Singapore

Tan Tock Seng Hospital, Communicable Disease Centre, Singapore, , Singapore

Hospital Universitari Vall d'Hebron, Barcelona, , Spain

Centro Integral Oncologico Clara Campal, Madrid, , Spain

Hospital Clinico Universitario de Valencia, Valencia, , Spain

Shuang Ho Hospital, New Taipei City, , Taiwan

Taichung Veterans General Hospital, The Radiation Oncology Department, Taichung, , Taiwan

National Cheng Kung University Hospital, Tainan, , Taiwan

National Taiwan University Hospital, Taipei, , Taiwan

Taipei Medical University Hospital (TMUH), Taipei, , Taiwan

Taipei Veterans General Hospital, Medical Science & Technology Building, Taipei, , Taiwan

Linkou Chang-Gung Memorial Hospital, Taoyuan, , Taiwan

CI Dnipropetrovsk CMCH #4 of Dnipropetrovsk RC Dept of Chemotherapy SI Dnipropetrovsk MA of MOHU, Dnipro, , Ukraine

SI V.T. Zaycev Institute of general & urgent surgery of National academy medical sciences of Ukraine, Department of purulent surgery, Kharkiv, , Ukraine

Communal Non-profit Enterprise Regional Center of Oncology, Kharkiv, , Ukraine

Ninewells Hospital, Dundee, , United Kingdom

Guy's Hospital, London, , United Kingdom

Hammersmith Hospital, London, , United Kingdom

The Christie, Manchester, , United Kingdom

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

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