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Brief Title: Study of AM003 in Patients With Locally Advanced and Metastatic Solid Tumors
Official Title: A Phase I, Open-Label Multicenter Study of AM003 Dose Escalation, Administered Intratumorally to Patients With Locally Advanced and Metastatic Solid Tumors
Study ID: NCT06258330
Brief Summary: This is a phase 1, first-in-human study to assess the safety and tolerability of AM003 in patients with locally advanced and metastatic solid tumors
Detailed Description: This is a phase 1, open-label , multicenter dose escalation trial evaluating the safety and tolerability of AM003 , administered intratumorally to patients with locally advanced and metastatic solid tumors
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Rambam Health Care Campus, Haifa, , Israel
Hadassah Medical Center, Jerusalem, , Israel
Rabin Medical Center, Petach Tikva, , Israel
Sheba Medical Center, Ramat Gan, , Israel
Tel Aviv Sourasky Medical Center, Tel Aviv, , Israel
Name: Irit Carmi Levy, PhD
Affiliation: GM and Chief Scientific Officer Aummune
Role: STUDY_CHAIR