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Brief Title: BGJ398 for Patients With Tumors With FGFR Genetic Alterations
Official Title: Modular Phase II Study to Link Targeted Therapy to Patients With Pathway Activated Tumors: Module 6 - BGJ398 for Patients With Tumors With FGFR Genetic Alterations
Study ID: NCT02160041
Brief Summary: The purpose of this signal seeking study was to determine whether treatment with BGJ398 demonstrates sufficient efficacy in select FGFR pathway-regulated solid tumors and/or hematologic malignancies to warrant further study.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Alabama Oncology St. Vincent's Birmingham, Birmingham, Alabama, United States
North County Oncology Medical Clinic Inc, Oceanside, California, United States
San Francisco General Hospital San Francisco Gen Hosp (7), San Francisco, California, United States
Rocky Mountain Cancer Centers Rocky Mountain Cancer Ctr (50), Greenwood Village, Colorado, United States
Norwalk Hospital, Norwalk, Connecticut, United States
Florida Cancer Specialists Florida Cancer Specialists 36, Fort Myers, Florida, United States
University of Miami Sylvester Comprehensive Cancer, Miami, Florida, United States
NorthWest Georgia Oncology Centers NW Georgia Oncology, Marietta, Georgia, United States
Harbin Clinic Medical Oncology Clin. Res., Rome, Georgia, United States
Illinois Cancer Specialists, Arlington Heights, Illinois, United States
Lurie Children's Hospital of Chicago Developmental Therapeutics, Chicago, Illinois, United States
Community Clinical Research Center, Anderson, Indiana, United States
Indiana University Indiana Univ. - Purdue Univ., Indianapolis, Indiana, United States
Northern Indiana Cancer Research Consortium No. Indiana Cancer Res., South Bend, Indiana, United States
University of Louisville / James Graham Brown Cancer Center SC, Louisville, Kentucky, United States
St. Agnes Hospital St. Agnes Hospital (2), Baltimore, Maryland, United States
Southcoast Centers for Cancer Care, Fairhaven, Massachusetts, United States
Cancer and Hematology Centers of West Michigan Dept. of Oncology, Grand Rapids, Michigan, United States
Minnesota Oncology Hematology, P.A. Minnesota Oncology Hem (27), Minneapolis, Minnesota, United States
Research Medical Center Research Med Center (2), Kansas City, Missouri, United States
Billings Clinic Billings Clinic (8), Billings, Montana, United States
Dartmouth Hitchcock Medical Center Dartmouth Hitchcock - Lebanon, Bedford, New Hampshire, United States
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
New Mexico Cancer Center, Albuquerque, New Mexico, United States
Waverly Hematology Oncology, Cary, North Carolina, United States
University of N C at Chapel Hill Physician Office Building, Chapel Hill, North Carolina, United States
Duke University Medical Center Seeley G. Mudd Bldg., Durham, North Carolina, United States
Wake Forest Baptist Health Hem & Onc Medical Center, Winston-Salem, North Carolina, United States
Sanford Hematology Oncology, Fargo, North Dakota, United States
Oncology Hematology Care Inc Oncology Hematology Care 2, Cincinnati, Ohio, United States
University Hospitals of Cleveland Seidman Cancer Center University Hospitals, Cleveland, Ohio, United States
Cleveland Clinic Foundation Taussig Cancer Institute, Cleveland, Ohio, United States
Bend Memorial Clinic Bend Mem. Clinic, Bend, Oregon, United States
Northwest Cancer Specialists Northwest Cancer, Portland, Oregon, United States
Lehigh Valley Health Network, Allentown, Pennsylvania, United States
Cancer Treatment Centers of America Eastern Regional Medical Center, Philadelphia, Pennsylvania, United States
University of Pittsburgh Cancer Institute Hillman Cancer Center (2), Pittsburgh, Pennsylvania, United States
Rhode Island Hospital Rhode Island Hosp. (2), Providence, Rhode Island, United States
Sanford University of South Dakota Medical Center Sanford Health, Sioux Falls, South Dakota, United States
Chattanooga Oncology and Hematology Assoicates, PC Chattanooga Oncology, Chattanooga, Tennessee, United States
Tennessee Oncology Tennessee Oncology (3), Nashville, Tennessee, United States
The Center for Cancer and Blood Disorders, Fort Worth, Texas, United States
Oncology Consultants Oncology Group, Houston, Texas, United States
Houston Methodist Cancer Center, Houston, Texas, United States
MD Anderson Cancer Center/University of Texas MD Anderson Cancer Center (3), Houston, Texas, United States
Texas Oncology, McAllen, Texas, United States
Cancer Therapy & Research Center UT Health Science Center Oncology Dept., San Antonio, Texas, United States
Texas Oncology Cancer Care & Research Center Texas Oncology, Waco, Texas, United States
Deke Slayton Cancer Center Deke Slayton Cancer Center (2), Webster, Texas, United States
Intermountain Medical Center Intermountain Healthcare, Murray, Utah, United States
Northern Utah Cancer Associates Northern Utah Assoc (3), Ogden, Utah, United States
University of Utah / Huntsman Cancer Institute SC-2, Salt Lake City, Utah, United States
Utah Cancer Specialists Utah Cancer Specialists (11), Salt Lake City, Utah, United States
Virginia Cancer Specialists Fairfax Northern Virginia, Fairfax, Virginia, United States
Shenandoah Oncology Shenandoah Oncology (5), Winchester, Virginia, United States
Northwest Medical Specialties NW Medical Specialties, Tacoma, Washington, United States