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Brief Title: Individualized Stereotactic Body Radiotherapy of Liver Metastases
Official Title: Phase II Study of Individualized Stereotactic Body Radiotherapy of Liver Metastases
Study ID: NCT01239381
Brief Summary: Stereotactic body radiation therapy (SBRT) is a technique that is used to deliver radiation, to sites in the body. All participants in this study will be treated with SBRT using proton beam radiation. Proton beam radiation uses tiny particles to deliver radiation to tumors. The purpose of this research study is to determine if SBRT with protons will prevent tumor growth and reduce the treatment side effects for liver metastases.
Detailed Description: * Participants receiving SBRT with protons, will receive radiation treatment as an outpatient at the Francis H. Burr Proton Therapy Center at Massachusetts General Hospital. * Not everyone who participates in this study will be receiving the same dose of radiation. The dose received will be determined by the size and location of the tumor(s). * Participants will receive 2-3 SBRT treatments per week for two weeks. * During radiation therapy visits the following tests/procedures will be performed: vital signs, physical examination, routine blood tests, research blood tests, and radiation planning. * Follow-up assessments will be performed once at 9 weeks after study treatment, then at 6 months, 12 months, 18 months and 24 months after treatment.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Massachusetts General Hospital, Boston, Massachusetts, United States
Dana-Farber Cancer Institue, Boston, Massachusetts, United States
Name: Theodore S. Hong, MD
Affiliation: Massachusetts General Hospital
Role: PRINCIPAL_INVESTIGATOR