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Spots Global Cancer Trial Database for A Phase II Study to Evaluate the Efficacy of TKI258 for the Treatment of Patients With FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometrial Cancer

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Trial Identification

Brief Title: A Phase II Study to Evaluate the Efficacy of TKI258 for the Treatment of Patients With FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometrial Cancer

Official Title: A Phase II, Open-label, Single-arm, Non-randomized, Multi-center Study to Evaluate the Efficacy of Oral TKI258 as Second-line Therapy in Patients With Either FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometrial Cancer

Study ID: NCT01379534

Interventions

TKI258

Study Description

Brief Summary: This is a prospective, multi-center, open-label, single-arm, non-randomized, Phase II study to evaluate the efficacy and safety of TKI258 as second-line therapy in patients with either FGFR2 mutated or wild-type advanced and/or metastatic endometrial cancer.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

University of South Alabama / Mitchell Cancer Institute Univ South Alabama, Mobile, Alabama, United States

St. Jude Heritage Medical Group St Jude, Fullerton, California, United States

USC/Kenneth Norris Comprehensive Cancer Center USC 2, Los Angeles, California, United States

Cedars Sinai Medical Center TKI258A2211 (SC), Los Angeles, California, United States

University of California at Los Angeles UCLA 3, Los Angeles, California, United States

Rocky Mountain Cancer Centers Dept. of Rocky Mountain Cancer, Greenwood Village, Colorado, United States

Florida Hospital Cancer Institute FL Hosp, Orlando, Florida, United States

Indiana University Health Goshen Center for Cancer IU Simon Cancer, Indianapolis, Indiana, United States

University of Iowa Hospitals & Clinics SC, Iowa City, Iowa, United States

Dana Farber Cancer Institute SC, Boston, Massachusetts, United States

Southeast Nebraska Oncology Cancer Center, Lincoln, Nebraska, United States

Hope A Woman's Cancer Center, Asheville, North Carolina, United States

Duke University Medical Center Duke3, Durham, North Carolina, United States

Community Oncology Research Network, Chattanooga, Tennessee, United States

The West Clinic SC, Memphis, Tennessee, United States

Texas Oncology, P.A. Austin, Bedford, Texas, United States

Texas Oncology, P.A. Tex Onc (3), Bedford, Texas, United States

Texas Oncology, P.A. SC, Fort Worth, Texas, United States

South Texas Oncology and Hematology, PA South Tex Onc, San Antonio, Texas, United States

Virginia Oncology Associates VOA - Lake Wright, *see Various Departments*, Virginia, United States

Cancer Care Northwest SC, Spokane, Washington, United States

Novartis Investigative Site, Belo Horizonte, MG, Brazil

Novartis Investigative Site, Porto Alegre, RS, Brazil

Novartis Investigative Site, Ribeirao Preto, SP, Brazil

Novartis Investigative Site, Genova, GE, Italy

Novartis Investigative Site, Monza, MB, Italy

Novartis Investigative Site, Milano, MI, Italy

Novartis Investigative Site, Milano, MI, Italy

Novartis Investigative Site, Pisa, PI, Italy

Novartis Investigative Site, Roma, RM, Italy

Novartis Investigative Site, Candiolo, TO, Italy

Novartis Investigative Site, Seoul, Korea, Korea, Republic of

Novartis Investigative Site, Seoul, , Korea, Republic of

Novartis Investigative Site, Grafton, Auckland, , New Zealand

Novartis Investigative Site, Cordoba, Andalucia, Spain

Novartis Investigative Site, Málaga, Andalucia, Spain

Novartis Investigative Site, Oviedo, Asturias, Spain

Novartis Investigative Site, Sabadell, Barcelona, Spain

Novartis Investigative Site, Barcelona, Catalunya, Spain

Novartis Investigative Site, Majadahonda, Madrid, Spain

Novartis Investigative Site, Murcia, , Spain

Novartis Investigative Site, Glasgow, , United Kingdom

Novartis Investigative Site, Leeds, , United Kingdom

Novartis Investigative Site, London, , United Kingdom

Novartis Investigative Site, Nottingham, , United Kingdom

Contact Details

Name: Novartis Pharmaceuticals

Affiliation: Novartis Pharmaceuticals

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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