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Brief Title: Open-Label Study to Assess the Safety/Tolerability in Patients With Solid Tumors
Official Title: A Phase I, Open-Label, Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of INCB007839 Following Multiple Oral Doses in Patients With Solid Tumors
Study ID: NCT00820560
Brief Summary: To establish the maximum tolerated dose (MTD) of INCB007839 given as multiple doses for 28 days and to determine if a higher MTD can be established when INCB007839 is administered in combination with prophylactic anticoagulation and with a 2 and a half day (5 doses) treatment interruption every two weeks.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Aurora, Colorado, United States
, Baltimore, Maryland, United States
, Philadelphia, Pennsylvania, United States
, Nashville, Tennessee, United States
Name: William V Williams, MD
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR