Spots Global Cancer Trial Database for A Study of DF6002 Alone and in Combination With Nivolumab
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Trial Identification
Brief Title: A Study of DF6002 Alone and in Combination With Nivolumab
Official Title: A Phase 1/2, First-In-Human, Multi-Part, Open-Label, Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological, and Clinical Activity of DF6002 as a Monotherapy and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion in Selected Indications
Study ID: NCT04423029
Conditions
Study Description
Brief Summary: The purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab in participants with advanced solid tumors.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Local Institution, Orange, California, United States
University of California Irvine, Orange, California, United States
SCRI - HealthOne Denver, Denver, Colorado, United States
Local Institution, New Haven, Connecticut, United States
Yale School of Medicine, New Haven, Connecticut, United States
Local Institution, Miami, Florida, United States
University of Miami, Miami, Florida, United States
Augusta University Georgia Cancer Center, Augusta, Georgia, United States
Local Institution, Augusta, Georgia, United States
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Local Institution, Boston, Massachusetts, United States
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States
Henry Ford Hospital, Detroit, Michigan, United States
Local Institution, Detroit, Michigan, United States
HealthPartners Cancer Center at Regions Hospital, Saint Paul, Minnesota, United States
Local Institution, Saint Paul, Minnesota, United States
Atlantic Health System, Morristown, New Jersey, United States
Local Institution, Bronx, New York, United States
Montefiore Medical Center, Bronx, New York, United States
Local Institution, Buffalo, New York, United States
Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States
Local Institution, Cleveland, Ohio, United States
University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
Local Institution, Oklahoma City, Oklahoma, United States
Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
Local Institution, Providence, Rhode Island, United States
Rhode Island Hospital, Providence, Rhode Island, United States
Local Institution, Nashville, Tennessee, United States
SCRI - Tennessee Oncology - Saint Thomas West Clinic, Nashville, Tennessee, United States
Local Institution, Houston, Texas, United States
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Huntsman Cancer Institute and Hospital, Salt Lake City, Utah, United States
Local Institution, Salt Lake City, Utah, United States
Local Institution, Fairfax, Virginia, United States
USOR - Virginia Cancer Specialists - Fairfax Office, Fairfax, Virginia, United States
Froedtert Hospital, Milwaukee, Wisconsin, United States
Local Institution - 0023, Box Hill, , Australia
Local Institution - 0022, Heidelberg, , Australia
Local Institution, Paris, Ile-de-France, France
Local Institution, Pierre-Bénite, Rhone, France
Local Institution - 0026, Bordeaux Cedex, , France
Local Institution - 0002, Paris, , France
Local Institution - 0027, Pierre-Benite, , France
Local Institution - 0001, Villejuif, , France
Local Institution, Pamplona, Navarre, Spain
Local Institution - 0029, Barcelona, , Spain
Local Institution, Madrid, , Spain
Local Institution - 0031, Madrid, , Spain
Local Institution - 0030, Madrid, , Spain
Local Institution, Madrid, , Spain
Local Institution - 0028, Madrid, , Spain
Local Institution - 0025, Pamplona, , Spain
Contact Details
Name: Jean-Marie Cuillerot, MD
Affiliation: Chief Medical Officer
Role: STUDY_DIRECTOR
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