Spots Global Cancer Trial Database for A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors
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Trial Identification
Brief Title: A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors
Official Title: A Phase 1 Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors
Study ID: NCT03762447
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of INCB086550 in participants with advanced solid tumors who have failed prior treatments.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Georgetown University Hospital, Washington, District of Columbia, United States
H. Lee Moffitt Cancer Center and Research Institute Hospital, Tampa, Florida, United States
Aamc Oncology and Hematology, Annapolis, Maryland, United States
University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States
Jefferson University Hospitals, Philadelphia, Pennsylvania, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States
Md Anderson Cancer Center, Houston, Texas, United States
Institut Jules Bordet, Brussels, , Belgium
Universitair Ziekenhuis Antwerpen (Uza), Edegem, , Belgium
Universitair Ziekenhuis Gent, Gent, , Belgium
Universitaire Ziekenhuis Leuven - Gasthuisberg, Leuven, , Belgium
Chu Hopital de La Timone, Marseille Cedex 5, , France
Icm Montpellier, Montpellier Cedex 5, , France
Institut Curie, Paris, , France
Institut Universitaire Du Cancer de Toulouse Oncopole, Toulouse, , France
Fondazione Irccs Istituto Nazionale Dei Tumori, Milan, , Italy
European Institute of Oncology, Milan, , Italy
Istituto Nazionale Tumori Irccs Fondazione Pascale, Napoli, , Italy
Irrcs Instituto Clinico Humanitas, Rozzano, , Italy
Azienda Ospedaliera Universitaria Senese Policlinico Santa Maria Alle Scotte, Siena, , Italy
Addenbrooke'S Hospital, Cambridge, , United Kingdom
Guys and St Thomas Nhs Foundation Trust, London, , United Kingdom
Imperial College Healthcare Nhs Trust - Hammersmith Hospital, London, , United Kingdom
The Christie Nhs Foundation Trust Uk, Manchester, , United Kingdom
Weston Park Hospital, Sheffield, , United Kingdom
Contact Details
Name: Kevin O'Hayer, MD, PhD
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR
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