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Brief Title: A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
Official Title: A Phase 1, Open-Label, Multicenter Study of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
Study ID: NCT05836324
Brief Summary: To evaluate the safety, tolerability, and DLTs and determine the MTD and/or RDE(s) of INCA33890 in participants with select advanced or metastatic solid tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The Angeles Clinic and Research Institute, Los Angeles, California, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Cancer and Hematology Centers of Western Michigan-Start Midwest, Grand Rapids, Michigan, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Lifespan Cancer Research Institute, Providence, Rhode Island, United States
University of Texas Md Anderson Cancer Center, Houston, Texas, United States
South Texas Accelerated Research Therapeutics, San Antonio, Texas, United States
Rigshospitalet Uni of Hospital of Copenhagen, Copenhagen, , Denmark
Herlev Og Gentofte Hospital, Herlev, , Denmark
Odense University Hospital, Odense C, , Denmark
Vejle Hospital, Vejle, , Denmark
Centre Leon Berard, Lyon, , France
Institut Paoli Calmettes, Marseille, , France
Institut Gustave Roussy, Villejuif Cedex, , France
Fondazione Irccs Istituto Nazionale Del Tumori Di Milano, Milano, , Italy
Irccs Istituto Clinico Humanitas, Rozzano, , Italy
Centro Ricerche Cliniche Di Verona (Crc), Verona, , Italy
Start Barcelona, Barcelona, , Spain
Hospital General Universitario Vall D Hebron, Barcelona, , Spain
Fundacion Jimenez Diaz University Hospital, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Centro Integral Oncologico Clara Campal, Madrid, , Spain
Istituto Oncologico Della Svizzera Italiana, Bellinzona, , Switzerland
Centre Hospitalier Universitaire Vaudois (Chuv), Lausanne, , Switzerland
Kantonsspital St. Gallen, St. Gallen, , Switzerland
Cambridge University Hospitals Nhs Foundation Trust, Cambridge, , United Kingdom
Guys and St Thomas Nhs Foundation Trust, London, , United Kingdom
Imperial College Healthcare Nhs Trust - Hammersmith Hospital, London, , United Kingdom
The Christie Nhs Foundation Trust Uk, Manchester, , United Kingdom
Freeman Hospital Newcastle Upon Tyne Foundation Nhs Trust, Newcastle Upon Tyne, , United Kingdom