Spots Global Cancer Trial Database for Genomic Profiling in Cancer Patients
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Trial Identification
Brief Title: Genomic Profiling in Cancer Patients
Official Title: Genomic Profiling in Cancer Patients
Study ID: NCT01775072
Study Description
Brief Summary: The purpose of this study is to determine whether certain genes in cancer may be abnormal. When a gene is abnormal this is called a mutation. Most mutations in cancer cells are not inherited (passed down from parents) but happen after birth in the cancer itself. Most cancers have many mutations. Some of these mutations are important for the cancer cells to survive while others are not. The goal of this study is test cancer for certain mutations using leftover tumor tissue from a previous surgery or biopsy. Participants will also be asked to provide a tube of blood cheek (also known as a buccal) swab, or a saliva sample that contains normal genes for comparison. The purpose of Part B of this study is to: Understand how genetic changes in tumor effect the chance of responding to experimental cancer treatment. Understand how the genes in the tumor change overtime in response to targeted cancer treatment.
Detailed Description:
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
St. Vincent (Data Collection Only), Bridgeport, Connecticut, United States
Hartford Healthcare Cancer Institute @ Hartford Hospital, Hartford, Connecticut, United States
Norwalk Hospital, Norwalk, Connecticut, United States
Baptist Alliance MCI, Miami, Florida, United States
Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth, Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen, Montvale, New Jersey, United States
NYC Health & Hospitals /Lincoln Medical Center, Bronx, New York, United States
New York Cancer & Blood Specialists (Data collection only), Bronx, New York, United States
Kings County Hopsital Center, Brooklyn, New York, United States
Memorial Sloan Kettering Cancer Commack, Commack, New York, United States
Memorial Sloan Kettering Westchester, Harrison, New York, United States
Queens Cancer Center of Queens Hospital, Jamaica, New York, United States
Metropolitan Hospital Center, New York, New York, United States
Ralph Lauren Center for Cancer Care and Prevention, New York, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Memorial Sloan Kettering Nassau, Uniondale, New York, United States
Lehigh Valley Health Network, Allentown, Pennsylvania, United States
Contact Details
Name: David Solit, MD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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